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ENZYME

ENZYME entry: EC 2.3.1.194

Accepted Name
acetoacetyl-CoA synthase
Alternative Name(s)
NphT7
Reaction catalysed
acetyl-CoA + H(+) + malonyl-CoA <=> acetoacetyl-CoA + CO2 + CoA
Comment(s)
  • The enzyme from the soil bacterium Streptomyces sp. CL190 produces acetoacetyl-CoA to be used for mevalonate production via the mevalonate pathway.
  • Unlike the homologous EC 2.3.1.180 this enzyme does not accept malonyl-[acyl-carrier-protein] as a substrate.
Cross-references
BRENDA2.3.1.194
EC2PDB2.3.1.194
ExplorEnz2.3.1.194
PRIAM enzyme-specific profiles2.3.1.194
KEGG Ligand Database for Enzyme Nomenclature2.3.1.194
IUBMB Enzyme Nomenclature2.3.1.194
IntEnz2.3.1.194
MEDLINEFind literature relating to 2.3.1.194
MetaCyc2.3.1.194
Rhea expert-curated reactions2.3.1.194
UniProtKB/Swiss-Prot
D7URV0, NPHT7_STRC1

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