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ENZYME

ENZYME entry: EC 5.1.1.18

Accepted Name
serine racemase
Reaction catalysed
L-serine <=> D-serine
Comment(s)
  • Highly selective for L-serine as substrate.
  • D-Serine is found in type-II astrocytes in mammalian brain, where it appears to be an endogenous ligand of the glycine site of N-methyl-D- aspartate (NMDA) receptors.
  • The reaction can also occur in the reverse direction but does so more slowly at physiological serine concentrations.
Cross-references
BRENDA5.1.1.18
EC2PDB5.1.1.18
ExplorEnz5.1.1.18
PRIAM enzyme-specific profiles5.1.1.18
KEGG Ligand Database for Enzyme Nomenclature5.1.1.18
IUBMB Enzyme Nomenclature5.1.1.18
IntEnz5.1.1.18
MEDLINEFind literature relating to 5.1.1.18
MetaCyc5.1.1.18
Rhea expert-curated reactions5.1.1.18
UniProtKB/Swiss-Prot
Q2PGG3, SRR_ARATHA0JNI4, SRR_BOVINQ54HH2, SRR_DICDI
Q9GZT4, SRR_HUMANQ9QZX7, SRR_MOUSEA2XWA9, SRR_ORYSI
Q7XSN8, SRR_ORYSJQ76EQ0, SRR_RATO59791, SRR_SCHPO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 5.1.1.-
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