ProtParam
User-provided sequence:
10 20 30 40 50 60
DLDDDIEMSD ENDDDGLTDA GITAEHNPLV ELCEEAEEPV NEDRSKGKKL VVNVTEKDKI
70 80 90 100 110 120
ENKLIRLALK NLIENQILRN LPRAGMDDSY GYKALFDKAE QTLNLKYHKD NQEFREEIEK
130 140 150 160 170 180
LRIDVIKHIA KRSLKNFIVI SSIRNLFEPR FHQRVAGMVL NKTSEQIKSG QQSNIFEAGL
190 200 210 220 230 240
NSTMIVICNS CDITKGQGST IRGDDLMQLM VTLVDPHAKE VEDFLLVSYP KYQLQNTLFG
250 260 270 280 290 300
GEDYGVYGAT TGLLKSVAYK ESLESCDVRI MMDEDNFLFG AVKKALETKG SGSLGLFLFS
310 320 330 340 350 360
APQRPNALGS RSLRVANSVA KIADMQGVVE SSLDREMHIL KENESESLKK VPIGTLRAAT
370 380 390 400 410 420
ESITDSDVVN QIMSNAGARR EEEAVQDELK EIQKKIDPIA FYRLDAATAT DYRREADLAK
430 440 450 460 470 480
NELEDLKKKA QTLEEHGHKE ENYRQRLPEL EEQLSAEKQR ALKLRDKTTS DADEDRELAK
490 500 510 520 530 540
IEVQILQLQR EKSDLEEPKS DRAVAVGACS IDVLDLASDP LRRYPLYRKA LQAATVLASD
550 560 570 580 590 600
LIRVGHHIEY KPQLGRLIAV TQRVSPEAVE IKQFRREFAG DKEVISRYEN NTTAGIVKLQ
610 620 630 640 650 660
GRSLAPKLIN AADDKGNGML MHIEDIFLVI LTKSEEIEKL VGKFREEFDG KYKAGATLAA
670 680 690 700 710 720
LDLSFLKAGQ LITPVDDDII RQAVGEIIAT KGIGPEGILC PNSKIRRALV RITSRIEEER
730 740 750 760 770 780
GIVPDLKGQR AQETMDIAYK SLYELPTNTD AGRSDIRTNG RLELAQQKIA EIDVQAEKFI
790 800 810 820 830 840
QQISSDNFLA FLIHDQAIFS DKQQKQIKAA DQLVKGLAYS PTIEAPAPQQ QPIRVLNRNV
850 860 870 880 890 900
VKKFLDYDYR GKEILNQLYP VSGDEPTEIF AALIHIPQLQ PHQHDSALKQ ALTLITLARE
TFQTQDNM
References and
documentation are available.
Number of amino acids: 908
Molecular weight: 102034.97
Theoretical pI: 5.31
Total number of negatively charged residues (Asp + Glu): 150
Total number of positively charged residues (Arg + Lys): 124
Atomic composition:
Carbon C 4480
Hydrogen H 7285
Nitrogen N 1259
Oxygen O 1411
Sulfur S 21
Formula: C
4480H
7285N
1259O
1411S
21
Total number of atoms: 14456
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 33155
Abs 0.1% (=1 g/l) 0.325, assuming all pairs of Cys residues form cystines
Ext. coefficient 32780
Abs 0.1% (=1 g/l) 0.321, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is D (Asp).
The estimated half-life is: 1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 46.99
This classifies the protein as unstable.
Aliphatic index: 95.43
Grand average of hydropathicity (GRAVY): -0.468