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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
DNRIHVINDV KILHNDIDRG NLLDNSRFKE RGEAITTVLG SQLHRKAVRE ETAEYDIDIK

70 80 90 100 110 120
YVLLAGTDAL TKYIKKWNEQ DYLLYLGELI VIRTFKSICY QDPTPDKLAH NFGPVFIDPI

130 140 150 160 170 180
TQSFTKSLKE FVSSTSYFKH HSSVKCLSTK ALIKCLQLFN NSDFTSPSGR RKHATQPDKF

190 200 210 220 230 240
LDLCRRSLHF GDMPVIQAIN ISDQALKNVN VPNDVAAIRI ANATGGRAVV ATCEENNSTL

250 260 270 280 290 300
ASYKVPQFNV DEVHDKFLGQ NEIMEAVKNP QLTKLSDVLN VMPKLRDNVE IVNPHESLFT

310 320 330 340 350
HYKENIIQCL EEAITSKGSG PSGVLIVCVR YNDEIRNDLL QLVDDALKHT DVM


References and documentation are available.

Number of amino acids: 353 Molecular weight: 39885.46 Theoretical pI: 6.33
Amino acid composition: 
Ala (A) 20 5.7% Arg (R) 16 4.5% Asn (N) 25 7.1% Asp (D) 27 7.6% Cys (C) 7 2.0% Gln (Q) 13 3.7% Glu (E) 19 5.4% Gly (G) 14 4.0% His (H) 12 3.4% Ile (I) 26 7.4% Leu (L) 35 9.9% Lys (K) 26 7.4% Met (M) 4 1.1% Phe (F) 14 4.0% Pro (P) 13 3.7% Ser (S) 23 6.5% Thr (T) 20 5.7% Trp (W) 1 0.3% Tyr (Y) 10 2.8% Val (V) 28 7.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 1768 Hydrogen H 2820 Nitrogen N 490 Oxygen O 537 Sulfur S 11 Formula: C1768H2820N490O537S11 Total number of atoms: 5626 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 20775 Abs 0.1% (=1 g/l) 0.521, assuming all pairs of Cys residues form cystines Ext. coefficient 20400 Abs 0.1% (=1 g/l) 0.511, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is D (Asp). The estimated half-life is: 1.1 hours (mammalian reticulocytes, in vitro). 3 min (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.39 This classifies the protein as stable. Aliphatic index: 96.06 Grand average of hydropathicity (GRAVY): -0.313