ProtParam

User-provided sequence:

        10         20         30         40         50         60 
IAGLYDEKIS GIAHISSVQS ICGEIKVRIR SKITIVDESS QYSPPNSGAN FTLDQPMLHK 

        70         80         90        100        110        120 
TVFVKMPGVQ VEFGHQSCSV VTGDVVEGKF PKFVVARYKV NFEASGDTPL IRGRQIDIND 

       130        140        150        160        170 
YDLVCLIYGF KGTCSGEVEE LLKTKLYQKM RPGFFSPHLT INLSLDKIFF M 

References and documentation are available.

Number of amino acids: 171

Molecular weight: 19058.06

Theoretical pI: 7.83

Amino acid composition: 
Ala (A)   5	  2.9%
Arg (R)   6	  3.5%
Asn (N)   5	  2.9%
Asp (D)   9	  5.3%
Cys (C)   4	  2.3%
Gln (Q)   7	  4.1%
Glu (E)   9	  5.3%
Gly (G)  14	  8.2%
His (H)   4	  2.3%
Ile (I)  15	  8.8%
Leu (L)  12	  7.0%
Lys (K)  13	  7.6%
Met (M)   4	  2.3%
Phe (F)  11	  6.4%
Pro (P)   8	  4.7%
Ser (S)  15	  8.8%
Thr (T)   8	  4.7%
Trp (W)   0	  0.0%
Tyr (Y)   6	  3.5%
Val (V)  16	  9.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 18
Total number of positively charged residues (Arg + Lys): 19

Atomic composition:

Carbon      C	       861
Hydrogen    H	      1356
Nitrogen    N	       222
Oxygen      O	       249
Sulfur      S	         8

Formula: C861H1356N222O249S8
Total number of atoms: 2696

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     9190
Abs 0.1% (=1 g/l)   0.482, assuming all pairs of Cys residues form cystines


Ext. coefficient     8940
Abs 0.1% (=1 g/l)   0.469, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is I (Ile).

The estimated half-life is: 20 hours (mammalian reticulocytes, in vitro).
                            30 min (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.52
This classifies the protein as stable.



Aliphatic index: 91.64

Grand average of hydropathicity (GRAVY): -0.009