ProtParam

User-provided sequence:

        10         20         30         40         50         60 
LEDLYPLNSV DGVAVYNFKG LKFDKVADFN LEIPSSVSEN QVANKLKTYN IAPSLDKGKK 

        70         80         90        100        110        120 
LDAVIKKINS SVVASDQDRV FLTFLGGDTF KDLKASSILG SLESLASTLY NALVEYQALS 

       130        140        150        160        170        180 
AKNVPIGIAA VSDGIFRVRN EEGLFFKPES KSVLSKGAPL TSLLSEDVFR KLDAEVVNEG 

       190        200        210        220        230        240 
SVELNEKTYV KDAFDKIDQL SVREVGDYLL PNGLGKRFTI AYLQDEASKV PCQEAVAYDY 

       250        260        270        280        290        300 
RAAPLVSETL EHPKFATKYL VDALANVYYP LDDKLFTAKL TIYERDLTSK FTGGLLESER 

       310        320        330        340        350        360 
VLKLASRTNT NQFNFRNLLH AVGDKTAYRS GGHVKVALTS IKTPADRASV TLRRVSGQAF 


QLRAASLM 

References and documentation are available.

Number of amino acids: 368

Molecular weight: 40478.15

Theoretical pI: 7.83

Amino acid composition: 
Ala (A)  35	  9.5%
Arg (R)  16	  4.3%
Asn (N)  18	  4.9%
Asp (D)  25	  6.8%
Cys (C)   1	  0.3%
Gln (Q)   9	  2.4%
Glu (E)  21	  5.7%
Gly (G)  20	  5.4%
His (H)   3	  0.8%
Ile (I)  12	  3.3%
Leu (L)  47	 12.8%
Lys (K)  31	  8.4%
Met (M)   1	  0.3%
Phe (F)  18	  4.9%
Pro (P)  12	  3.3%
Ser (S)  32	  8.7%
Thr (T)  19	  5.2%
Trp (W)   0	  0.0%
Tyr (Y)  15	  4.1%
Val (V)  33	  9.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 47

Atomic composition:

Carbon      C	      1823
Hydrogen    H	      2908
Nitrogen    N	       480
Oxygen      O	       554
Sulfur      S	         2

Formula: C1823H2908N480O554S2
Total number of atoms: 5767

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    22350
Abs 0.1% (=1 g/l)   0.552, assuming all pairs of Cys residues form cystines


Ext. coefficient    22350
Abs 0.1% (=1 g/l)   0.552, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is L (Leu).

The estimated half-life is: 5.5 hours (mammalian reticulocytes, in vitro).
                            3 min (yeast, in vivo).
                            2 min (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 20.41
This classifies the protein as stable.



Aliphatic index: 98.04

Grand average of hydropathicity (GRAVY): -0.148