ProtParam

User-provided sequence:

        10         20         30         40         50         60 
PDEDELLIPN DRGEDWVSDQ SQNNEDGYNS LLQANSGKST ASTRPIGRTP SSFAVDDIDV 

        70         80         90        100        110        120 
LKENLEKDVN QLIKGLSDNN GNSEQTNDHN KEAVNPLSSG ILNVDSDDRN VIGSTNKSES 

       130        140        150        160        170        180 
NVGLRSDQET DSIVINTNNP SSQREMSDTS LSQVHSSLQP IKKSPYIRKP KPSPMMIDHT 

       190        200        210        220        230        240 
SSLAQDNKIP SSVGEFQKAR TKLSPRGFYP STFEEQETEN ASESIFPSSS KLINHRIPPS 

       250        260        270        280        290        300 
VSATEPSAAR VPDENDTIIE GTPQRVVSNH LETPERETTS ISSSRSCPPE STLQANNDKS 

       310        320        330        340        350        360 
SQDINEIIQI EEDDDDYNEN NNINTSKKEE MQMVEEYLNE KKLYSIYNLQ LLKLTHRLNK 

       370        380        390        400        410        420 
RASNRENKDF YKNIMKATFH KSKIKSNKWV DITEVPNEFF KRINLIVHVG CDSMNPQQPV 

       430        440        450        460        470        480 
PCTKMKIQTK DLQISYKDLA YSILFEKIPD IERSHTQRLS DFTLINVLPN NISIEDSNIA 

       490        500        510        520        530        540 
DNKDKNQHFD LIADLNTIIC SFWHYSINIP IVVYKKSFLD TNNVWKKVNS YYDAPNSILK 

       550        560        570        580        590        600 
TYFFSSMLHV QERKIISKEI SSEIYFKTFF DLISDNVWDK NFLCKFDQNT ITYSSGDNFK 

       610        620        630        640        650        660 
YCLSPKFLEP TEFETTADDF ESNSNSNAPD SVDKFRNSRR LQSVAHSQLT ETGNTNYFDS 

       670        680        690        700        710        720 
PSINSKPVSI SHEKKGLSAI RTRKTLSQLG HPKNSLFHTH IQPSEDDNTS LKTKKLRLSD 

       730        740        750        760        770        780 
FANKTSNIAR EMNLSPSSSS IPHILHKLRE LIQEKHDLIE VKISSSYSML LFRKISKIKK 

       790        800        810        820        830        840 
NSASSATSWI LINTNINISS NNVDLIMKVK KLDKLIIAMF SNKKDLIILE VDDLLNVQSN 

       850        860        870        880        890        900 
YIVSQQFYLS FKPHNHDSVF TMICPAKHRY IRLTKSDVCS FQGNLNLKTS IISGNPSTSA 

       910        920        930        940        950        960 
VAPEPSGNGL NNSMQFLLGN STSKLSSHRK LPSSQLPEFD QDSCGSNVGE GEDNNDVDND 

       970        980        990       1000       1010       1020 
SLEIQRKSES NMSLVPLFDK TSANNLHDVI KPDKRFTNYR KPPLSASSRP SSARSSNLTD 

      1030 
LPKLSNFKRK RASM 

References and documentation are available.

Number of amino acids: 1034

Molecular weight: 116882.54

Theoretical pI: 6.39

Amino acid composition: 
Ala (A)  33	  3.2%
Arg (R)  40	  3.9%
Asn (N)  98	  9.5%
Asp (D)  73	  7.1%
Cys (C)   9	  0.9%
Gln (Q)  39	  3.8%
Glu (E)  60	  5.8%
Gly (G)  25	  2.4%
His (H)  25	  2.4%
Ile (I)  79	  7.6%
Leu (L)  83	  8.0%
Lys (K)  85	  8.2%
Met (M)  17	  1.6%
Phe (F)  40	  3.9%
Pro (P)  53	  5.1%
Ser (S) 146	 14.1%
Thr (T)  55	  5.3%
Trp (W)   6	  0.6%
Tyr (Y)  24	  2.3%
Val (V)  44	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 133
Total number of positively charged residues (Arg + Lys): 125

Atomic composition:

Carbon      C	      5097
Hydrogen    H	      8100
Nitrogen    N	      1432
Oxygen      O	      1663
Sulfur      S	        26

Formula: C5097H8100N1432O1663S26
Total number of atoms: 16318

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    69260
Abs 0.1% (=1 g/l)   0.593, assuming all pairs of Cys residues form cystines


Ext. coefficient    68760
Abs 0.1% (=1 g/l)   0.588, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is P (Pro).

The estimated half-life is: >20 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            ? (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.04
This classifies the protein as unstable.



Aliphatic index: 76.63

Grand average of hydropathicity (GRAVY): -0.717