ProtParam

User-provided sequence:

        10         20         30         40         50         60 
PQQQQQQQQE KDHAVQEMYL THNVLNLYAY MFNSLLVQER LGRKSNSLKL HSLRYIAREV 

        70         80         90        100        110        120 
NIPLRHDFMI VTSVTLLPLP FGFASDTFQV PSNPKDPKKV DAFTLKRPPL ISTHKLPPAA 

       130        140        150        160        170        180 
PAQTQASAEV PASTQVPASN QVPASAQVPV STQVQEQAPA QLQAKQEDTN EKQVHKSHQQ 

       190        200        210        220        230        240 
NSIETTNSRK KNKKKAEEEE RDRSNSKTSS VSVAPQLQPL SESDSEEKKE IEIAGELQPQ 

       250        260        270        280        290        300 
LPIQQQPQSD KLTKVSIKQS GHRSHHHRHP RPRNRLVIPE VPERGSKNGL KKSKRVRVHV 

       310        320        330        340        350        360 
ADNNPISPSS SPSSSPSSSA DHKHHPKRRF LNAFTKEIKQ RTQSTATSTS SNNMEEKNSV 

       370        380        390        400        410        420 
ETKEGGNFLS IYHKKSNDLE MRQSDVNEEN EDDGQNEEND DERSMKNNLW TWGNRRRHRK 

       430        440        450        460        470        480 
TEKNDDTASP KVMDTTGERL ELDQEVTDNR VKVPVEEAEK EIGMEQEWEG SSQRYHNYID 

       490        500        510        520        530        540 
QFDGISGPSS MNESDEDQQR FPSKHPDIEV KITNKTLKLR EEDDNKMEDV SQEVEKEQEQ 

       550        560        570        580        590        600 
SRIRYTNFRS RRLSSREPWT MTNNIPMNSA FEGDDLTNAQ STSFGIDGED YHGEPQPQDK 

       610        620        630        640        650        660 
KDSYSGAMSL TRALTIADND TLGASNSIKT LEETIDRLSV PREKIKSIRE EVKNVTESAS 

       670        680        690        700        710        720 
DGKNDDDEND DFETYSRRLT SPRRILSANG HRSLGRNLNI TNNEKNEYSQ SEKDEGNDEI 

       730        740        750        760        770        780 
DNNENSNGDN DEGNDSLQIN QLTDQVLELF NDPKVNPHQN APVWLLNKKL VNANLKRSPS 

       790        800        810        820        830        840 
HVGKKIGLYN GQKTKNSSEI GSNGRGHLNE LPTPDSYRTN NVTTTDSPMS ASSSTTGSWS 

       850        860        870        880        890        900 
RRGSSEGGFK IDLEPDILLD MSGISLRKLN KVSRIENDLS QAAILVESKR KDRQSAIAKD 

       910 
SSTTRLMSEN DRNSM 

References and documentation are available.

Number of amino acids: 915

Molecular weight: 103358.41

Theoretical pI: 5.96

Amino acid composition: 
Ala (A)  41	  4.5%
Arg (R)  58	  6.3%
Asn (N)  75	  8.2%
Asp (D)  62	  6.8%
Cys (C)   0	  0.0%
Gln (Q)  58	  6.3%
Glu (E)  81	  8.9%
Gly (G)  38	  4.2%
His (H)  25	  2.7%
Ile (I)  38	  4.2%
Leu (L)  62	  6.8%
Lys (K)  69	  7.5%
Met (M)  17	  1.9%
Phe (F)  17	  1.9%
Pro (P)  50	  5.5%
Ser (S) 107	 11.7%
Thr (T)  53	  5.8%
Trp (W)   6	  0.7%
Tyr (Y)  14	  1.5%
Val (V)  44	  4.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 143
Total number of positively charged residues (Arg + Lys): 127

Atomic composition:

Carbon      C	      4387
Hydrogen    H	      7055
Nitrogen    N	      1347
Oxygen      O	      1509
Sulfur      S	        17

Formula: C4387H7055N1347O1509S17
Total number of atoms: 14315

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    53860
Abs 0.1% (=1 g/l)   0.521

Estimated half-life:

The N-terminal of the sequence considered is P (Pro).

The estimated half-life is: >20 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            ? (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 61.77
This classifies the protein as unstable.



Aliphatic index: 61.05

Grand average of hydropathicity (GRAVY): -1.172