ProtParam

User-provided sequence:

        10         20         30         40         50         60 
RQQPQTHMYG VNEMRRNVAR TTPQLSNIVR QHHLTTSSGM PGRLLNRANQ SATHGVSHNT 

        70         80         90        100        110        120 
STTRNKNIPN VDKNFLYSES KWIGSLVAQI KASALHPYLD DFKKDYNTFL LDDEDKHDTD 

       130        140        150        160        170        180 
SSSHAISQAD NHSKKRINNA NGTIIPQVRL LAEDLPNYFR KVNSYEHSIR EFERKADING 

       190        200        210        220        230        240 
AMFISDSGDN QSSLDMISNE RQLWLKRQTR SEADIGDSKL FQAFSNFKAG SNSQRNADSG 

       250        260        270        280        290        300 
SNTSSTIHEN SLPSAPAASN KNLDNSRLLL NQNGKKHFIN NMRSGHFSEP AARRLNNTLS 

       310        320        330        340        350        360 
SISTSFNHQP VNNDKSGINA ITPFTSQSNP INQGLQSRGG NKKSKRLKGD DLENFTDGSA 

       370        380        390        400        410        420 
MHEGSDHIEN GLSNQISSSN EFRREVGTSQ SLIMNPAYNE LLSHGEIDKT GASSIDDPKI 

       430        440        450        460        470        480 
LDEEENLLKH QKSSQRRLSM FSSDSKRSSN SRPADIHDEQ DFQEDSHSPK QNSKHAALTN 

       490        500        510        520        530        540 
GVDLIKKEKD YPAESINDGA KVLSARLNQS HSSLDDIDAE KTVKSQGEEN IVSTANLKTE 

       550        560        570        580        590        600 
ISSPSTEGDK QHEISHSSEG FYNNSSLHPL PLSVARHNEK GDTGSKDEEQ EDISDPSQLE 

       610        620        630        640        650        660 
NQNLQQVNKK EEPMVHEAIV KDNNVKGDEI NDESFCEVEE DTTSESKKSE QADRLSLVSQ 

       670        680        690        700        710        720 
TSKSRRPKLG FGATGTNSHS SNKPSLLTNH VPSHFSASRK GQNSKVRTLA TMNLGSITRK 

       730        740        750        760        770        780 
RFLADSSKCK QSVNHKNFYD NDLTGDHTLV RRLGKFSANS KARSRTSFQR FPKSQHSVTS 

       790 
ANLSTVDTDS KLTRGRHVM 

References and documentation are available.

Number of amino acids: 799

Molecular weight: 88845.17

Theoretical pI: 7.91

Amino acid composition: 
Ala (A)  43	  5.4%
Arg (R)  45	  5.6%
Asn (N)  74	  9.3%
Asp (D)  55	  6.9%
Cys (C)   2	  0.3%
Gln (Q)  40	  5.0%
Glu (E)  47	  5.9%
Gly (G)  40	  5.0%
His (H)  34	  4.3%
Ile (I)  36	  4.5%
Leu (L)  59	  7.4%
Lys (K)  58	  7.3%
Met (M)  12	  1.5%
Phe (F)  26	  3.3%
Pro (P)  27	  3.4%
Ser (S) 117	 14.6%
Thr (T)  44	  5.5%
Trp (W)   2	  0.3%
Tyr (Y)  10	  1.3%
Val (V)  28	  3.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 102
Total number of positively charged residues (Arg + Lys): 103

Atomic composition:

Carbon      C	      3766
Hydrogen    H	      6020
Nitrogen    N	      1176
Oxygen      O	      1289
Sulfur      S	        14

Formula: C3766H6020N1176O1289S14
Total number of atoms: 12265

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    26025
Abs 0.1% (=1 g/l)   0.293, assuming all pairs of Cys residues form cystines


Ext. coefficient    25900
Abs 0.1% (=1 g/l)   0.292, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is R (Arg).

The estimated half-life is: 1 hours (mammalian reticulocytes, in vitro).
                            2 min (yeast, in vivo).
                            2 min (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.33
This classifies the protein as unstable.



Aliphatic index: 61.91

Grand average of hydropathicity (GRAVY): -1.014