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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
SKVKKKVQKK RLIILRVDKL YVKSRCLACH GFQRCTRSSN VMQFLCPCCF VHGCLTMLAT

70 80 90 100 110 120
EPPEFCIPCR YDKAAGYEKP AEKTEEQFDD DSIQLVQQEE ADLDIADATL DVTQEKSNTG

130 140 150 160 170 180
PKTTPPAADL MPSASPTNAT QSLVDMTHLE EVNNTLTINN GSSAEPEETH MTERDHNGSD

190 200 210 220 230 240
NNSTNHDSGP DEELARFLSL DDDGDEESTN ELAREGIIEV VAEPSDHRND TVINQTRSVE

250 260 270
NEEEEDNQRV SELRVRKIRL NEGEPNQNDP RRAM


References and documentation are available.

Number of amino acids: 274 Molecular weight: 30763.88 Theoretical pI: 4.66
Amino acid composition: 
Ala (A) 17 6.2% Arg (R) 17 6.2% Asn (N) 19 6.9% Asp (D) 23 8.4% Cys (C) 9 3.3% Gln (Q) 12 4.4% Glu (E) 31 11.3% Gly (G) 10 3.6% His (H) 7 2.6% Ile (I) 10 3.6% Leu (L) 20 7.3% Lys (K) 14 5.1% Met (M) 6 2.2% Phe (F) 6 2.2% Pro (P) 15 5.5% Ser (S) 19 6.9% Thr (T) 20 7.3% Trp (W) 0 0.0% Tyr (Y) 3 1.1% Val (V) 16 5.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 54 Total number of positively charged residues (Arg + Lys): 31 Atomic composition: Carbon C 1292 Hydrogen H 2074 Nitrogen N 384 Oxygen O 456 Sulfur S 15 Formula: C1292H2074N384O456S15 Total number of atoms: 4221 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 4970 Abs 0.1% (=1 g/l) 0.162, assuming all pairs of Cys residues form cystines Ext. coefficient 4470 Abs 0.1% (=1 g/l) 0.145, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is S (Ser). The estimated half-life is: 1.9 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.52 This classifies the protein as unstable. Aliphatic index: 65.84 Grand average of hydropathicity (GRAVY): -0.885