ProtParam

User-provided sequence:

        10         20         30         40         50         60 
YFTSPRKYSF TKTSKQVRHP LPFKLDKTLF QKVYQRKVDA TKEIEAVKLI HISRFRARHR 

        70         80         90        100        110        120 
AAMDQYLTEV AAVRSVDRIE KYMNHTGSRS DYRVWVGFNK VKTPHAENIQ NISVIEGSAK 

       130        140        150        160        170 
KVKHLKQLFY WYRSKAIVEN SAFIRMRFLK PEPVSETPLR RGIVQYEKFH AMKWKQPM 

References and documentation are available.

Number of amino acids: 178

Molecular weight: 21235.76

Theoretical pI: 10.34

Amino acid composition: 
Ala (A)  12	  6.7%
Arg (R)  16	  9.0%
Asn (N)   5	  2.8%
Asp (D)   5	  2.8%
Cys (C)   0	  0.0%
Gln (Q)   8	  4.5%
Glu (E)  10	  5.6%
Gly (G)   4	  2.2%
His (H)   7	  3.9%
Ile (I)  10	  5.6%
Leu (L)   9	  5.1%
Lys (K)  21	 11.8%
Met (M)   5	  2.8%
Phe (F)  10	  5.6%
Pro (P)   8	  4.5%
Ser (S)  12	  6.7%
Thr (T)   9	  5.1%
Trp (W)   3	  1.7%
Tyr (Y)   9	  5.1%
Val (V)  15	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 15
Total number of positively charged residues (Arg + Lys): 37

Atomic composition:

Carbon      C	       968
Hydrogen    H	      1525
Nitrogen    N	       277
Oxygen      O	       252
Sulfur      S	         5

Formula: C968H1525N277O252S5
Total number of atoms: 3027

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29910
Abs 0.1% (=1 g/l)   1.408

Estimated half-life:

The N-terminal of the sequence considered is Y (Tyr).

The estimated half-life is: 2.8 hours (mammalian reticulocytes, in vitro).
                            10 min (yeast, in vivo).
                            2 min (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.25
This classifies the protein as unstable.



Aliphatic index: 72.81

Grand average of hydropathicity (GRAVY): -0.661