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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
APLSLANSLT NLLSSSNGNL SVPQTPTKEH HPTAPTSNRK CDLPRSNSTT ISQLTKDRLK

70 80 90 100 110 120
NMIANRSKGE SNSQSNLMSN SVTANGNGHD NGRKLKNSNS QVNVSSPHFE PYRLPTSLAN

130 140 150 160 170 180
AHNLQQASEF QLRKVNSEPN LKMRIRAKLL SKGSSPVQHV QQNNSQFNFT HPQLKRSDSE

190 200 210 220 230 240
TSQNVPLDFM QSSSQTNLPH LMLPSPSLPN LAAAGAFHGL NLPVGQDLNA FMAVANLSPF

250 260 270 280 290 300
LSLPSLLNKK LELGGLTDEG DRNGLIGSSS TSSLASNVSM GSHQYQSLLK QQIRDLVLRR

310 320 330 340 350 360
KSLVREDPEG EGLAELYNGL LPQAKLQQLQ ALAAESGFLA KQEPTCTTGL GYDQAMVRHE

370 380 390 400 410 420
CCCGNNASHV ENGGRIQSIW SKLIEHGHVQ KCEKVTAKKA SLEQLQLVHS QTYTTFFAVS

430 440 450 460 470 480
PTACLKIDAN SLPLKRFLQL PCGGIGVDSD TYFNDASTQT AARLAAGTLI ELSSQVAEGR

490 500 510 520 530 540
LKNGFACIRP PGHHAEHEQA MGFCFFNNVA VAVKVLQTKY PAQCAKIAII DWDVHHGNGT

550 560 570 580 590 600
QLSFENDPNV LYMSLHRHDK GNFFPGTGSV TEVGKNDAKG LTVNVPFSGD VMRDPEYLAA

610 620 630 640 650 660
WRTVIEPVMA SFCPDFIIVS AGFDACHGHP NALGGYEVTP EMFGYMTKSL LNYASGKVVL

670 680 690 700 710 720
ALEGGYDLKS ISEAAQQCVQ ALIGESDDAG RLSSVALESL PNPSAVETLQ KVIAIHKSYW

730 740 750
PALHGQEAAI NTTEMQWRNL KLQVQMQQQQ QQQQT


References and documentation are available.

Number of amino acids: 755 Molecular weight: 82049.54 Theoretical pI: 7.71
Amino acid composition: 
Ala (A) 63 8.3% Arg (R) 26 3.4% Asn (N) 53 7.0% Asp (D) 27 3.6% Cys (C) 14 1.9% Gln (Q) 54 7.2% Glu (E) 36 4.8% Gly (G) 52 6.9% His (H) 26 3.4% Ile (I) 23 3.0% Leu (L) 85 11.3% Lys (K) 38 5.0% Met (M) 16 2.1% Phe (F) 25 3.3% Pro (P) 40 5.3% Ser (S) 76 10.1% Thr (T) 39 5.2% Trp (W) 5 0.7% Tyr (Y) 14 1.9% Val (V) 43 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 63 Total number of positively charged residues (Arg + Lys): 64 Atomic composition: Carbon C 3578 Hydrogen H 5683 Nitrogen N 1035 Oxygen O 1118 Sulfur S 30 Formula: C3578H5683N1035O1118S30 Total number of atoms: 11444 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 49235 Abs 0.1% (=1 g/l) 0.600, assuming all pairs of Cys residues form cystines Ext. coefficient 48360 Abs 0.1% (=1 g/l) 0.589, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is A (Ala). The estimated half-life is: 4.4 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.20 This classifies the protein as unstable. Aliphatic index: 80.65 Grand average of hydropathicity (GRAVY): -0.375