ProtParam
User-provided sequence:
10 20 30 40 50 60
GKVFKARDLK NGGRFVALKR VRVQTGEEGM PLSTIREVAV LRHLETFEHP NVVRLFDVCT
70 80 90 100 110
VSRTDRETKL TLVFEHVDQD LTTYLDKVPE PGVPTETIKD MMFQLLRGLD F
References and
documentation are available.
Number of amino acids: 111
Molecular weight: 12743.75
Theoretical pI: 7.04
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 17
Atomic composition:
Carbon C 568
Hydrogen H 919
Nitrogen N 159
Oxygen O 165
Sulfur S 4
Formula: C
568H
919N
159O
165S
4
Total number of atoms: 1815
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.117, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.117, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is G (Gly).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 27.57
This classifies the protein as stable.
Aliphatic index: 91.98
Grand average of hydropathicity (GRAVY): -0.269