ProtParam

User-provided sequence:

        10         20 
GRKRRQTSLT DFYHSKRRLV FCKRKP 

References and documentation are available.

Number of amino acids: 26

Molecular weight: 3264.85

Theoretical pI: 11.73

Amino acid composition: 
Ala (A)   0	  0.0%
Arg (R)   6	 23.1%
Asn (N)   0	  0.0%
Asp (D)   1	  3.8%
Cys (C)   1	  3.8%
Gln (Q)   1	  3.8%
Glu (E)   0	  0.0%
Gly (G)   1	  3.8%
His (H)   1	  3.8%
Ile (I)   0	  0.0%
Leu (L)   2	  7.7%
Lys (K)   4	 15.4%
Met (M)   0	  0.0%
Phe (F)   2	  7.7%
Pro (P)   1	  3.8%
Ser (S)   2	  7.7%
Thr (T)   2	  7.7%
Trp (W)   0	  0.0%
Tyr (Y)   1	  3.8%
Val (V)   1	  3.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 1
Total number of positively charged residues (Arg + Lys): 10

Atomic composition:

Carbon      C	       143
Hydrogen    H	       239
Nitrogen    N	        51
Oxygen      O	        35
Sulfur      S	         1

Formula: C143H239N51O35S1
Total number of atoms: 469

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     1490
Abs 0.1% (=1 g/l)   0.456, assuming all pairs of Cys residues form cystines


Ext. coefficient     1490
Abs 0.1% (=1 g/l)   0.456, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is G (Gly).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 110.18
This classifies the protein as unstable.



Aliphatic index: 41.15

Grand average of hydropathicity (GRAVY): -1.508