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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAACLLRYLV RQSRKPRSLV VSRESSHCSR MSTYSTVTNL STVKMQRIQH LAAFRSGVSL

70 80 90 100 110 120
AERVLNPPQQ SINGNHVSGN IQCSSDNNNK DTNAAFELAI KQLNSLQSND AAIRNSMSNS

130 140 150 160 170 180
RVDTKADTIK YLERSGLPLE TVEQLSFIHV AGTKGKGSTC ALTESLLRHQ GFRTGFFSSP

190 200 210 220 230 240
HILFTNERIR IDGQLLSKDK FTEQFWKVYN RLWDLREHDH DMPAYFKFLT ILGFHVFVAE

250 260 270 280 290 300
NVDVVVLEVG IGGEHDCTNI VRNVRTVGIT SLGLEHTELL GRTLPEIAWQ KAGIIKTGSH

310 320 330 340 350 360
VFTHVTQPEC LEVIRQRTKE HSATLYEVPP TEDYFRSKAY APIWQTFSNL IRLNGSLAIQ

370 380 390 400 410 420
LAQDWLSQSG KQQHTPNEVK MDPQLLDGLI STHWPGRCQL IEWHGMRLHL DGAHTLESME

430 440 450 460 470 480
VCTDWFEKNV RDSVNPKILI FNRTGESGFA PLLKLLNRTC DFDMVCFVPN LATSTPNAPS

490 500 510 520 530 540
QVMVRFSPEM QLNRARIIAS AWSDLCATEQ KKDVGQVYNT LTDAFTAIRQ RFPQATDNEG

550 560 570
QLEVLVTGSI HLLGAAISAL DLIDDPKSRT DK


References and documentation are available.

Number of amino acids: 572 Molecular weight: 64317.16 Theoretical pI: 7.65
Amino acid composition: 
Ala (A) 36 6.3% Arg (R) 36 6.3% Asn (N) 30 5.2% Asp (D) 29 5.1% Cys (C) 11 1.9% Gln (Q) 30 5.2% Glu (E) 31 5.4% Gly (G) 31 5.4% His (H) 20 3.5% Ile (I) 31 5.4% Leu (L) 60 10.5% Lys (K) 25 4.4% Met (M) 11 1.9% Phe (F) 24 4.2% Pro (P) 22 3.8% Ser (S) 47 8.2% Thr (T) 42 7.3% Trp (W) 9 1.6% Tyr (Y) 9 1.6% Val (V) 38 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 60 Total number of positively charged residues (Arg + Lys): 61 Atomic composition: Carbon C 2836 Hydrogen H 4496 Nitrogen N 814 Oxygen O 851 Sulfur S 22 Formula: C2836H4496N814O851S22 Total number of atoms: 9019 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 63535 Abs 0.1% (=1 g/l) 0.988, assuming all pairs of Cys residues form cystines Ext. coefficient 62910 Abs 0.1% (=1 g/l) 0.978, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.62 This classifies the protein as stable. Aliphatic index: 87.60 Grand average of hydropathicity (GRAVY): -0.298