ProtParam
User-provided sequence:
10 20 30 40 50 60
MAACLLRYLV RQSRKPRSLV VSRESSHCSR MSTYSTVTNL STVKMQRIQH LAAFRSGVSL
70 80 90 100 110 120
AERVLNPPQQ SINGNHVSGN IQCSSDNNNK DTNAAFELAI KQLNSLQSND AAIRNSMSNS
130 140 150 160 170 180
RVDTKADTIK YLERSGLPLE TVEQLSFIHV AGTKGKGSTC ALTESLLRHQ GFRTGFFSSP
190 200 210 220 230 240
HILFTNERIR IDGQLLSKDK FTEQFWKVYN RLWDLREHDH DMPAYFKFLT ILGFHVFVAE
250 260 270 280 290 300
NVDVVVLEVG IGGEHDCTNI VRNVRTVGIT SLGLEHTELL GRTLPEIAWQ KAGIIKTGSH
310 320 330 340 350 360
VFTHVTQPEC LEVIRQRTKE HSATLYEVPP TEDYFRSKAY APIWQTFSNL IRLNGSLAIQ
370 380 390 400 410 420
LAQDWLSQSG KQQHTPNEVK MDPQLLDGLI STHWPGRCQL IEWHGMRLHL DGAHTLESME
430 440 450 460 470 480
VCTDWFEKNV RDSVNPKILI FNRTGESGFA PLLKLLNRTC DFDMVCFVPN LATSTPNAPS
490 500 510 520 530 540
QVMVRFSPEM QLNRARIIAS AWSDLCATEQ KKDVGQVYNT LTDAFTAIRQ RFPQATDNEG
550 560 570
QLEVLVTGSI HLLGAAISAL DLIDDPKSRT DK
References and
documentation are available.
Number of amino acids: 572
Molecular weight: 64317.16
Theoretical pI: 7.65
Total number of negatively charged residues (Asp + Glu): 60
Total number of positively charged residues (Arg + Lys): 61
Atomic composition:
Carbon C 2836
Hydrogen H 4496
Nitrogen N 814
Oxygen O 851
Sulfur S 22
Formula: C
2836H
4496N
814O
851S
22
Total number of atoms: 9019
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 63535
Abs 0.1% (=1 g/l) 0.988, assuming all pairs of Cys residues form cystines
Ext. coefficient 62910
Abs 0.1% (=1 g/l) 0.978, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 39.62
This classifies the protein as stable.
Aliphatic index: 87.60
Grand average of hydropathicity (GRAVY): -0.298