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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAELVSSAT SEKLADVDWA KNIEICELAA RDERQAKDVI KAIKKRLGSK NPNTQLYAVQ

70 80 90 100 110 120
LLEMLMNNIG ENIHKQVIDT GVLPTLVKIV KKKSDLPVRE RIFLLLDATQ TSLGGASGKF

130 140 150 160 170 180
PQYYTAYYEL VNAGVKFTQR PNATPVVVTA QAVPRNTLNE QLASARNEGP ATTQQRESQS

190 200 210 220 230 240
VSPSSILQKA STALEILKEV LDAVDSQNPE GAKDEFTLDL VEQCSFQKER VMHLVMTSRD

250 260 270 280 290 300
EKAVSKAIEL NEQLQRILNR HEDLLSGRIT VPSRSTTSNG YHSNLEPVRP ISNGDQKREL

310 320 330 340 350 360
KASNANTESS SFISNRAHLK LEEEDEEEEP EQLFRRLRKG KARARPEDEE EPSPPQGLPG

370 380 390 400 410 420
SAIHNERLNR PLIRPLPSEE ASRGGDSHSQ SPPVVIPPPP AKHVEREKFF KENKGDGALG

430 440
LPGHMRGLSL HSRDGSSSRS GSVDFSD


References and documentation are available.

Number of amino acids: 447 Molecular weight: 49422.53 Theoretical pI: 6.27
Amino acid composition: 
Ala (A) 35 7.8% Arg (R) 31 6.9% Asn (N) 23 5.1% Asp (D) 21 4.7% Cys (C) 2 0.4% Gln (Q) 22 4.9% Glu (E) 43 9.6% Gly (G) 24 5.4% His (H) 10 2.2% Ile (I) 19 4.3% Leu (L) 44 9.8% Lys (K) 29 6.5% Met (M) 6 1.3% Phe (F) 10 2.2% Pro (P) 29 6.5% Ser (S) 44 9.8% Thr (T) 20 4.5% Trp (W) 1 0.2% Tyr (Y) 6 1.3% Val (V) 28 6.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 64 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 2140 Hydrogen H 3485 Nitrogen N 635 Oxygen O 691 Sulfur S 8 Formula: C2140H3485N635O691S8 Total number of atoms: 6959 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14565 Abs 0.1% (=1 g/l) 0.295, assuming all pairs of Cys residues form cystines Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.292, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.53 This classifies the protein as unstable. Aliphatic index: 80.96 Grand average of hydropathicity (GRAVY): -0.676