ProtParam
User-provided sequence:
10 20 30 40 50 60
MAAIRDYKTA LDLTKSLPRP DGLSVQELMD SKIRGGLAYN DFLILPGLVD FASSEVSLQT
70 80 90 100 110 120
KLTRNITLNI PLVSSPMDTV TESEMATFMA LLDGIGFIHH NCTPEDQADM VRRVKNYENG
130 140 150 160 170 180
FINNPIVISP TTTVGEAKSM KEKYGFAGFP VTADGKRNAK LVGAITSRDI QFVEDNSLLV
190 200 210 220 230 240
QDVMTKNPVT GAQGITLSEG NEILKKIKKG RLLVVDEKGN LVSMLSRTDL MKNQKYPLAS
250 260 270 280 290 300
KSANTKQLLW GASIGTMDAD KERLRLLVKA GLDVVILDSS QGNSIFQLNM IKWIKETFPD
310 320 330 340 350 360
LEIIAGNVVT KEQAANLIAA GADGLRIGMG TGSICITQKV MACGRPQGTA VYNVCEFANQ
370 380 390 400
FGVPCMADGG VQKHWSYYYQ SFGSWFFYCY DGWYVGRYYR ITR
References and
documentation are available.
Number of amino acids: 403
Molecular weight: 44386.14
Theoretical pI: 8.36
Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 44
Atomic composition:
Carbon C 1974
Hydrogen H 3145
Nitrogen N 529
Oxygen O 589
Sulfur S 21
Formula: C
1974H
3145N
529O
589S
21
Total number of atoms: 6258
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 48735
Abs 0.1% (=1 g/l) 1.098, assuming all pairs of Cys residues form cystines
Ext. coefficient 48360
Abs 0.1% (=1 g/l) 1.090, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 31.69
This classifies the protein as stable.
Aliphatic index: 90.00
Grand average of hydropathicity (GRAVY): -0.101