ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAIYSLYII NKSGGLIFYK DCGTKGRMDT NDSLRVASLW HSMHAISQQL SPVNGCSGIE 

        70         80         90        100        110        120 
LLEADTFDLH CFQSLPGTKF FVVCEPGTPH MESLLRYIYE LYTDYVLKNP FYEIEMPIRC 

       130        140 
ELFDINLTQA VQSDRVALLG R 

References and documentation are available.

Number of amino acids: 141

Molecular weight: 16011.44

Theoretical pI: 5.24

Amino acid composition: 
Ala (A)   7	  5.0%
Arg (R)   6	  4.3%
Asn (N)   5	  3.5%
Asp (D)   8	  5.7%
Cys (C)   5	  3.5%
Gln (Q)   5	  3.5%
Glu (E)   8	  5.7%
Gly (G)   9	  6.4%
His (H)   4	  2.8%
Ile (I)  10	  7.1%
Leu (L)  17	 12.1%
Lys (K)   5	  3.5%
Met (M)   5	  3.5%
Phe (F)   7	  5.0%
Pro (P)   6	  4.3%
Ser (S)  11	  7.8%
Thr (T)   7	  5.0%
Trp (W)   1	  0.7%
Tyr (Y)   8	  5.7%
Val (V)   7	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 16
Total number of positively charged residues (Arg + Lys): 11

Atomic composition:

Carbon      C	       720
Hydrogen    H	      1111
Nitrogen    N	       183
Oxygen      O	       210
Sulfur      S	        10

Formula: C720H1111N183O210S10
Total number of atoms: 2234

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    17670
Abs 0.1% (=1 g/l)   1.104, assuming all pairs of Cys residues form cystines


Ext. coefficient    17420
Abs 0.1% (=1 g/l)   1.088, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.79
This classifies the protein as unstable.



Aliphatic index: 94.04

Grand average of hydropathicity (GRAVY): 0.033