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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAKHEYNKL SLVHLPRKEV HSEKRIPSIL TRTIAVLFVF ALLALVSIGS EGVPQLRNSR

70 80 90 100 110 120
DLTKSPCKKR VVGYYSEWEG TEITRSQLGK LTHAVFAFIH MDSEGKLQFK TNQKERFEKL

130 140 150 160 170 180
KTAVKNANSD TKVMISIGGD HNSENFGSVL SDSEKKSMFI DSIARFIRQH KIHGVDIYWK

190 200 210 220 230 240
WLGNSETEHH DFPSFLKDLK EKLKTVRDDS IISIVAPQAK MDRRHDGYKF DDFMEYIDFV

250 260 270 280 290 300
NVFSMDYYGP WPNQWGTPTG PSAPLYGGIG VKKHFNVDST MKYYTCMTED PSKFNMVIPF

310 320 330 340 350 360
YVRLWKNVKE PISSGTEVFR RADLKNGAAV GNSYMSRWTV DHEGWELTPA LWDDVTKTPY

370 380 390 400 410 420
VWNQETGNFL TFENKKSIEA KLAYAIEHNL GGVWIHLVDK DNENEELLRA VASKKFCASE


SENKVTYDC


References and documentation are available.

Number of amino acids: 429 Molecular weight: 49240.01 Theoretical pI: 8.12
Amino acid composition: 
Ala (A) 23 5.4% Arg (R) 18 4.2% Asn (N) 22 5.1% Asp (D) 26 6.1% Cys (C) 4 0.9% Gln (Q) 8 1.9% Glu (E) 30 7.0% Gly (G) 25 5.8% His (H) 15 3.5% Ile (I) 23 5.4% Leu (L) 30 7.0% Lys (K) 40 9.3% Met (M) 11 2.6% Phe (F) 22 5.1% Pro (P) 16 3.7% Ser (S) 34 7.9% Thr (T) 24 5.6% Trp (W) 11 2.6% Tyr (Y) 16 3.7% Val (V) 31 7.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 56 Total number of positively charged residues (Arg + Lys): 58 Atomic composition: Carbon C 2220 Hydrogen H 3412 Nitrogen N 594 Oxygen O 646 Sulfur S 15 Formula: C2220H3412N594O646S15 Total number of atoms: 6887 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 84590 Abs 0.1% (=1 g/l) 1.718, assuming all pairs of Cys residues form cystines Ext. coefficient 84340 Abs 0.1% (=1 g/l) 1.713, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.50 This classifies the protein as unstable. Aliphatic index: 74.50 Grand average of hydropathicity (GRAVY): -0.500