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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAKKVFGSA EASNLVTELR RSFDDGVTRG YEWRVTQLKK LMIICDNHEP EIVAALRDDL

70 80 90 100 110 120
GKPELESSVY EVSLLRNSIK LALKQLKNWM APEKAKTSLT TFPASAEIVS EPLGVVLVIS

130 140 150 160 170 180
AWNYPFLLSI DPVIGAISAG NAVVLKPSEL APASSALLTK LLEQYLDPSA VRVVEGAVTE

190 200 210 220 230 240
TSALLEQKWD KIFYTGSSKI GRVIMAAAAK HLTPVVLELG GKSPVVVDSD TDLKVTVRRI

250 260 270 280 290 300
IVGKWGCNNG QACVSPDYIL TTKEYAPKLI DAMKLELEKF YGKNPIESKD MSRIVNSNHF

310 320 330 340 350 360
DRLSKLLDEK EVSDKIVYGG EKDRENLKIA PTILLDVPLD SLIMSEEIFG PLLPILTLNN

370 380 390 400 410 420
LEESFDVIRS RPKPLAAYLF THNKKLKERF AATVSAGGIV VNDIAVHLAL HTLPFGGVGE

430 440 450 460 470 480
SGMGAYHGKF SFDAFSHKKA VLYRSLFGDS AVRYPPYSRG KLRLLKALVD SNIFDLFKVL


LGLA


References and documentation are available.

Number of amino acids: 484 Molecular weight: 53158.80 Theoretical pI: 8.43
Amino acid composition: 
Ala (A) 42 8.7% Arg (R) 20 4.1% Asn (N) 17 3.5% Asp (D) 26 5.4% Cys (C) 3 0.6% Gln (Q) 5 1.0% Glu (E) 31 6.4% Gly (G) 30 6.2% His (H) 8 1.7% Ile (I) 28 5.8% Leu (L) 63 13.0% Lys (K) 40 8.3% Met (M) 8 1.7% Phe (F) 18 3.7% Pro (P) 24 5.0% Ser (S) 40 8.3% Thr (T) 20 4.1% Trp (W) 5 1.0% Tyr (Y) 14 2.9% Val (V) 42 8.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 57 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 2414 Hydrogen H 3879 Nitrogen N 627 Oxygen O 695 Sulfur S 11 Formula: C2414H3879N627O695S11 Total number of atoms: 7626 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 48485 Abs 0.1% (=1 g/l) 0.912, assuming all pairs of Cys residues form cystines Ext. coefficient 48360 Abs 0.1% (=1 g/l) 0.910, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.04 This classifies the protein as stable. Aliphatic index: 107.17 Grand average of hydropathicity (GRAVY): 0.048