ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAASETVLRV PLGSVSQSCY LASFFVNSTP NLSFKPVSRN RKTVRCTNSH EVSSVPKHSF 

        70         80         90        100        110        120 
HSSNSVLKGK KFVSTICKCQ KHDVEESIRS TLLPSDGLSS ELKSDLDEMP LPVNGSVSSN 

       130        140        150        160        170        180 
GNAQSVGTKS IEDEAWDLLR QSVVFYCGSP IGTIAANDPN STSVLNYDQV FIRDFIPSGI 

       190        200        210        220        230        240 
AFLLKGEYDI VRNFILYTLQ LQSWEKTMDC HSPGQGLMPC SFKVKTVPLD GDDSMTEEVL 

       250        260        270        280        290        300 
DPDFGEAAIG RVAPVDSGLW WIILLRAYGK CTGDLSVQER VDVQTGIKMI LKLCLADGFD 

       310        320        330        340        350        360 
MFPTLLVTDG SCMIDRRMGI HGHPLEIQAL FYSALVCARE MLTPEDGSAD LIRALNNRLV 

       370        380        390        400        410        420 
ALNFHIREYY WLDLKKINEI YRYQTEEYSY DAVNKFNIYP DQIPSWLVDF MPNRGGYLIG 

       430        440        450        460        470        480 
NLQPAHMDFR FFTLGNLWSI VSSLASNDQS HAILDFIEAK WAELVADMPL KICYPAMEGE 

       490        500        510        520        530        540 
EWRIITGSDP KNTPWSYHNG GAWPTLLWQL TVASIKMGRP EIAEKAVELA ERRISLDKWP 

       550        560        570        580        590        600 
EYYDTKRARF IGKQARLYQT WSIAGYLVAK LLLANPAAAK FLTSEEDSDL RNAFSCMLSA 

       610 
NPRRTRGPKK AQQPFIV 

References and documentation are available.

Number of amino acids: 617

Molecular weight: 69240.19

Theoretical pI: 5.86

Amino acid composition: 
Ala (A)  43	  7.0%
Arg (R)  31	  5.0%
Asn (N)  27	  4.4%
Asp (D)  38	  6.2%
Cys (C)  13	  2.1%
Gln (Q)  20	  3.2%
Glu (E)  33	  5.3%
Gly (G)  36	  5.8%
His (H)  11	  1.8%
Ile (I)  37	  6.0%
Leu (L)  63	 10.2%
Lys (K)  32	  5.2%
Met (M)  16	  2.6%
Phe (F)  26	  4.2%
Pro (P)  33	  5.3%
Ser (S)  57	  9.2%
Thr (T)  28	  4.5%
Trp (W)  14	  2.3%
Tyr (Y)  21	  3.4%
Val (V)  38	  6.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 71
Total number of positively charged residues (Arg + Lys): 63

Atomic composition:

Carbon      C	      3104
Hydrogen    H	      4827
Nitrogen    N	       825
Oxygen      O	       913
Sulfur      S	        29

Formula: C3104H4827N825O913S29
Total number of atoms: 9698

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   109040
Abs 0.1% (=1 g/l)   1.575, assuming all pairs of Cys residues form cystines


Ext. coefficient   108290
Abs 0.1% (=1 g/l)   1.564, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.62
This classifies the protein as unstable.



Aliphatic index: 88.04

Grand average of hydropathicity (GRAVY): -0.172