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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAATAATTTS SHLLLSSSRH VASSSQPSIL SPRSLFSNNG KRAPTGVRNH QYASGVRCMA

70 80 90 100 110 120
VAADAAETKT AARKKSGYEL QTLTGWLLRQ EMKGEIDAEL TIVMSSISLA CKQIASLVQR

130 140 150 160 170 180
AGISNLTGVQ GAVNIQGEDQ KKLDVISNEV FSNCLRSSGR TGIIASEEED VPVAVEESYS

190 200 210 220 230 240
GNYVVVFDPL DGSSNIDAAV STGSIFGIYS PNDECIVDDS DDISALGSEE QRCIVNVCQP

250 260 270 280 290 300
GNNLLAAGYC MYSSSVIFVL TLGKGVFSFT LDPMYGEFVL TQENIEIPKA GRIYSFNEGN

310 320 330 340 350 360
YQMWDDKLKK YIDDLKDPGP TGKPYSARYI GSLVGDFHRT LLYGGIYGYP RDAKSKNGKL

370 380 390 400 410
RLLYECAPMS FIVEQAGGKG SDGHSRVLDI QPTEIHQRVP LYIGSTEEVE KLEKYLA


References and documentation are available.

Number of amino acids: 417 Molecular weight: 45161.89 Theoretical pI: 5.25
Amino acid composition: 
Ala (A) 32 7.7% Arg (R) 18 4.3% Asn (N) 17 4.1% Asp (D) 23 5.5% Cys (C) 8 1.9% Gln (Q) 16 3.8% Glu (E) 26 6.2% Gly (G) 37 8.9% His (H) 6 1.4% Ile (I) 27 6.5% Leu (L) 35 8.4% Lys (K) 21 5.0% Met (M) 8 1.9% Phe (F) 11 2.6% Pro (P) 16 3.8% Ser (S) 46 11.0% Thr (T) 20 4.8% Trp (W) 2 0.5% Tyr (Y) 19 4.6% Val (V) 29 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 1981 Hydrogen H 3137 Nitrogen N 539 Oxygen O 634 Sulfur S 16 Formula: C1981H3137N539O634S16 Total number of atoms: 6307 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39810 Abs 0.1% (=1 g/l) 0.881, assuming all pairs of Cys residues form cystines Ext. coefficient 39310 Abs 0.1% (=1 g/l) 0.870, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.98 This classifies the protein as unstable. Aliphatic index: 85.83 Grand average of hydropathicity (GRAVY): -0.208