ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAVTLHLRA ETKPLEARAA LTPTTVKKLI AKGFKIYVED SPQSTFNINE YRQAGAIIVP 

        70         80         90        100        110        120 
AGSWKTAPRD RIIIGLKEMP ETDTFPLVHE HIQFAHCYKD QAGWQNVLMR FIKGHGTLYD 

       130        140        150        160        170        180 
LEFLENDQGR RVAAFGFYAG FAGAALGVRD WAFKQTHSDD EDLPAVSPYP NEKALVKDVT 

       190        200        210        220        230        240 
KDYKEALATG ARKPTVLIIG ALGRCGSGAI DLLHKVGIPD ANILKWDIKE TSRGGPFDEI 

       250        260        270        280        290        300 
PQADIFINCI YLSKPIAPFT NMEKLNNPNR RLRTVVDVSA DTTNPHNPIP IYTVATVFNK 

       310        320        330        340        350        360 
PTVLVPTTAG PKLSVISIDH LPSLLPREAS EFFSHDLLPS LELLPQRKTA PVWVRAKKLF 

       370 
DRHCARVKRS SRL 

References and documentation are available.

Number of amino acids: 373

Molecular weight: 41464.83

Theoretical pI: 9.18

Amino acid composition: 
Ala (A)  37	  9.9%
Arg (R)  22	  5.9%
Asn (N)  14	  3.8%
Asp (D)  22	  5.9%
Cys (C)   4	  1.1%
Gln (Q)   9	  2.4%
Glu (E)  18	  4.8%
Gly (G)  21	  5.6%
His (H)  11	  2.9%
Ile (I)  25	  6.7%
Leu (L)  35	  9.4%
Lys (K)  26	  7.0%
Met (M)   4	  1.1%
Phe (F)  17	  4.6%
Pro (P)  28	  7.5%
Ser (S)  17	  4.6%
Thr (T)  25	  6.7%
Trp (W)   5	  1.3%
Tyr (Y)   9	  2.4%
Val (V)  24	  6.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 40
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      1878
Hydrogen    H	      2967
Nitrogen    N	       515
Oxygen      O	       528
Sulfur      S	         8

Formula: C1878H2967N515O528S8
Total number of atoms: 5896

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    41160
Abs 0.1% (=1 g/l)   0.993, assuming all pairs of Cys residues form cystines


Ext. coefficient    40910
Abs 0.1% (=1 g/l)   0.987, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.71
This classifies the protein as stable.



Aliphatic index: 91.31

Grand average of hydropathicity (GRAVY): -0.210