ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAWCSPRWL RVAVGTPRLP AAAGRGVQQP QGGVVAASLC RKLCVSAFGL SMGAHGPRAL 

        70         80         90        100        110        120 
LTLRPGVRLT GTKSFPFVCT ASFHTSASLA KDDYYQILGV PRNASQKDIK KAYYQLAKKY 

       130        140        150        160        170        180 
HPDTNKDDPK AKEKFSQLAE AYEVLSDEVK RKQYDAYGSA GFDPGASSSG QGYWRGGPSV 

       190        200        210        220        230        240 
DPEELFRKIF GEFSSSPFGD FQNVFDQPQE ETINTGPFVM RSTCRRCGGR GSIITNPCVV 

       250        260        270        280        290        300 
CRGAGQAKQK KRVTVPVPAG VEDGQTVRMP VGKREIFVTF RVQKSPVFRR DGADIHSDLF 

       310        320        330        340        350        360 
ISIAQAILGG TAKAQGLYET INVTIPAGIQ TDQKIRLTGK GIPRINSYGY GDHYIHIKIR 

       370        380        390        400        410        420 
VPKRLSSRQQ NLILSYAEDE TDVEGTVNGV THTSTGGRTM DSSTGSKDRR EAGEDNEGFL 


SKLKKIFTS 

References and documentation are available.

Number of amino acids: 429

Molecular weight: 46773.05

Theoretical pI: 9.57

Amino acid composition: 
Ala (A)  34	  7.9%
Arg (R)  31	  7.2%
Asn (N)  10	  2.3%
Asp (D)  23	  5.4%
Cys (C)   8	  1.9%
Gln (Q)  22	  5.1%
Glu (E)  18	  4.2%
Gly (G)  45	 10.5%
His (H)   7	  1.6%
Ile (I)  22	  5.1%
Leu (L)  24	  5.6%
Lys (K)  29	  6.8%
Met (M)   5	  1.2%
Phe (F)  19	  4.4%
Pro (P)  24	  5.6%
Ser (S)  34	  7.9%
Thr (T)  27	  6.3%
Trp (W)   3	  0.7%
Tyr (Y)  14	  3.3%
Val (V)  30	  7.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 60

Atomic composition:

Carbon      C	      2061
Hydrogen    H	      3268
Nitrogen    N	       600
Oxygen      O	       619
Sulfur      S	        13

Formula: C2061H3268N600O619S13
Total number of atoms: 6561

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    37860
Abs 0.1% (=1 g/l)   0.809, assuming all pairs of Cys residues form cystines


Ext. coefficient    37360
Abs 0.1% (=1 g/l)   0.799, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.51
This classifies the protein as unstable.



Aliphatic index: 70.02

Grand average of hydropathicity (GRAVY): -0.452