ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAWCSPRWL RVAVGTPRLP AAAGRGVQQP QGGVVAASLC RKLCVSAFGL SMGAHGPRAL 

        70         80         90        100        110        120 
LTLRPGVRLT GTKSFPFVCT ASFHTSASLA KDDYYQILGV PRNASQKDIK KAYYQLAKKY 

       130        140        150        160        170        180 
HPDTNKDDPK AKEKFSQLAE AYEVLSDEVK RKQYDAYGSA GFDPGASSSG QGYWRGGPSV 

       190        200        210        220        230        240 
DPEELFRKIF GEFSSSPFGD FQNVFDQPQE YIMELTFNQA AKGVNKEFTV NIMDTCERCD 

       250        260        270        280        290        300 
GKGNEPGTKV QHCHYCSGSG METINTGPFV MRSTCRRCGG RGSIITNPCV VCRGAGQAKQ 

       310        320        330        340        350        360 
KKRVTVPVPA GVEDGQTVRM PVGKREIFVT FRVQKSPVFR RDGADIHSDL FISIAQAILG 

       370        380        390        400        410        420 
GTAKAQGLYE TINVTIPAGI QTDQKIRLTG KGIPRINSYG YGDHYIHIKI RVPKRLSSRQ 

       430        440        450        460        470        480 
QNLILSYAED ETDVEGTVNG VTHTSTGGRT MDSSTGSKDR REAGEDNEGF LSKLKKIFTS 

References and documentation are available.

Number of amino acids: 480

Molecular weight: 52399.41

Theoretical pI: 9.34

Amino acid composition: 
Ala (A)  36	  7.5%
Arg (R)  32	  6.7%
Asn (N)  14	  2.9%
Asp (D)  25	  5.2%
Cys (C)  12	  2.5%
Gln (Q)  24	  5.0%
Glu (E)  22	  4.6%
Gly (G)  51	 10.6%
His (H)   9	  1.9%
Ile (I)  24	  5.0%
Leu (L)  25	  5.2%
Lys (K)  33	  6.9%
Met (M)   8	  1.7%
Phe (F)  21	  4.4%
Pro (P)  25	  5.2%
Ser (S)  36	  7.5%
Thr (T)  31	  6.5%
Trp (W)   3	  0.6%
Tyr (Y)  16	  3.3%
Val (V)  33	  6.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 47
Total number of positively charged residues (Arg + Lys): 65

Atomic composition:

Carbon      C	      2298
Hydrogen    H	      3636
Nitrogen    N	       668
Oxygen      O	       696
Sulfur      S	        20

Formula: C2298H3636N668O696S20
Total number of atoms: 7318

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    41090
Abs 0.1% (=1 g/l)   0.784, assuming all pairs of Cys residues form cystines


Ext. coefficient    40340
Abs 0.1% (=1 g/l)   0.770, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.12
This classifies the protein as stable.



Aliphatic index: 67.25

Grand average of hydropathicity (GRAVY): -0.465