ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAAYAAALFF WGWLGDRLNP KLVVAAGMVG SAVTLTLFGA IPKWFNFYHA PYYIMTYVAF 

        70         80         90        100        110        120 
GLVQACGWPS EIAIMANWFG KGNRGFVMGV WAACQPVGNI FGSIFTAMVL PLGYQYTFVF 

       130        140        150        160        170        180 
NSVLIALGAI VVVMAIDSSP NEEHEDGVEA NSSEPHHNFH GEPISLFKAV LLPGVLAYCI 

       190        200        210        220        230        240 
CNACLKLVNY AFFFWLPLYL TDAYHWEESQ ADQLSIWYDF GGIIGSVLGG YITDKMGKRS 

       250        260        270        280        290        300 
PLIVAMLVCS IGSLYFYAHV GPHMFWNAVV MTTVGVTVSG PYNLIVGSIS IDLGSQPALA 

       310        320        330        340        350        360 
GNTQAMSTVS GLLDGTGSAG SAVGQLLIPI IQDDLGWKAV FYVFMLLNGF AILAILKRCI 

       370        380 
IDLKSLRKLR SGEESPLLND EAGDHED 

References and documentation are available.

Number of amino acids: 387

Molecular weight: 41980.77

Theoretical pI: 5.16

Amino acid composition: 
Ala (A)  39	 10.1%
Arg (R)   6	  1.6%
Asn (N)  16	  4.1%
Asp (D)  15	  3.9%
Cys (C)   7	  1.8%
Gln (Q)   9	  2.3%
Glu (E)  13	  3.4%
Gly (G)  40	 10.3%
His (H)   9	  2.3%
Ile (I)  27	  7.0%
Leu (L)  42	 10.9%
Lys (K)  11	  2.8%
Met (M)  13	  3.4%
Phe (F)  23	  5.9%
Pro (P)  17	  4.4%
Ser (S)  26	  6.7%
Thr (T)  13	  3.4%
Trp (W)  11	  2.8%
Tyr (Y)  17	  4.4%
Val (V)  33	  8.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 28
Total number of positively charged residues (Arg + Lys): 17

Atomic composition:

Carbon      C	      1948
Hydrogen    H	      2936
Nitrogen    N	       470
Oxygen      O	       525
Sulfur      S	        20

Formula: C1948H2936N470O525S20
Total number of atoms: 5899

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    86205
Abs 0.1% (=1 g/l)   2.053, assuming all pairs of Cys residues form cystines


Ext. coefficient    85830
Abs 0.1% (=1 g/l)   2.045, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.54
This classifies the protein as stable.



Aliphatic index: 104.34

Grand average of hydropathicity (GRAVY): 0.535