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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MACLHTYIYI YIYIYNRTTC TRPWHTPSKD RLFECILHFL SQLARIRAPA NGCTFEDGPC

70 80 90 100 110 120
LLGLPKSASP SSRRRVFIGD SAYCRDHPRR NGLIRTRKVK LISVGRRVSF FSRRRPFIGP


ETV


References and documentation are available.

Number of amino acids: 123 Molecular weight: 14292.69 Theoretical pI: 10.51
Amino acid composition: 
Ala (A) 6 4.9% Arg (R) 18 14.6% Asn (N) 3 2.4% Asp (D) 4 3.3% Cys (C) 6 4.9% Gln (Q) 1 0.8% Glu (E) 3 2.4% Gly (G) 7 5.7% His (H) 4 3.3% Ile (I) 10 8.1% Leu (L) 10 8.1% Lys (K) 4 3.3% Met (M) 1 0.8% Phe (F) 7 5.7% Pro (P) 9 7.3% Ser (S) 10 8.1% Thr (T) 8 6.5% Trp (W) 1 0.8% Tyr (Y) 6 4.9% Val (V) 5 4.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 7 Total number of positively charged residues (Arg + Lys): 22 Atomic composition: Carbon C 639 Hydrogen H 1012 Nitrogen N 194 Oxygen O 166 Sulfur S 7 Formula: C639H1012N194O166S7 Total number of atoms: 2018 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14815 Abs 0.1% (=1 g/l) 1.037, assuming all pairs of Cys residues form cystines Ext. coefficient 14440 Abs 0.1% (=1 g/l) 1.010, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 77.72 This classifies the protein as unstable. Aliphatic index: 80.08 Grand average of hydropathicity (GRAVY): -0.293