ProtParam
User-provided sequence:
10 20 30 40 50 60
MACLHTYIYI YIYIYNRTTC TRPWHTPSKD RLFECILHFL SQLARIRAPA NGCTFEDGPC
70 80 90 100 110 120
LLGLPKSASP SSRRRVFIGD SAYCRDHPRR NGLIRTRKVK LISVGRRVSF FSRRRPFIGP
ETV
References and
documentation are available.
Number of amino acids: 123
Molecular weight: 14292.69
Theoretical pI: 10.51
Total number of negatively charged residues (Asp + Glu): 7
Total number of positively charged residues (Arg + Lys): 22
Atomic composition:
Carbon C 639
Hydrogen H 1012
Nitrogen N 194
Oxygen O 166
Sulfur S 7
Formula: C
639H
1012N
194O
166S
7
Total number of atoms: 2018
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14815
Abs 0.1% (=1 g/l) 1.037, assuming all pairs of Cys residues form cystines
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 1.010, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 77.72
This classifies the protein as unstable.
Aliphatic index: 80.08
Grand average of hydropathicity (GRAVY): -0.293