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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MADDKEMPAA VVDGHDQVTG HIISTTIGGK NGEPKQTISY MAERVVGTGS FGIVFQAKCL

70 80 90 100 110 120
ETGETVAIKK VLQDRRYKNR ELQLMRVMDH PNVVCLKHCF FSTTSKDELF LNLVMEYVPE

130 140 150 160 170 180
SLYRVLKHYS SANQRMPLVY VKLYMYQIFR GLAYIHNVAG VCHRDLKPQN LLVDPLTHQV

190 200 210 220 230 240
KICDFGSAKQ LVKGEANISY ICSRFYRAPE LIFGATEYTT SIDIWSAGCV LAELLLGQPL

250 260 270 280 290 300
FPGENAVDQL VEIIKVLGTP TREEIRCMNP HYTDFRFPQI KAHPWHKIFH KRMPPEAIDF

310 320 330 340 350 360
ASRLLQYSPS LRCTALEACA HPFFDELREP NARLPNGRPF PPLFNFKQEV AGSSPELVNK

370 380
LIPDHIKRQL GLSFLNQSGT


References and documentation are available.

Number of amino acids: 380 Molecular weight: 43098.90 Theoretical pI: 8.43
Amino acid composition: 
Ala (A) 24 6.3% Arg (R) 21 5.5% Asn (N) 15 3.9% Asp (D) 16 4.2% Cys (C) 10 2.6% Gln (Q) 17 4.5% Glu (E) 23 6.1% Gly (G) 22 5.8% His (H) 14 3.7% Ile (I) 22 5.8% Leu (L) 38 10.0% Lys (K) 22 5.8% Met (M) 10 2.6% Phe (F) 20 5.3% Pro (P) 25 6.6% Ser (S) 20 5.3% Thr (T) 18 4.7% Trp (W) 2 0.5% Tyr (Y) 14 3.7% Val (V) 27 7.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1942 Hydrogen H 3039 Nitrogen N 527 Oxygen O 543 Sulfur S 20 Formula: C1942H3039N527O543S20 Total number of atoms: 6071 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 32485 Abs 0.1% (=1 g/l) 0.754, assuming all pairs of Cys residues form cystines Ext. coefficient 31860 Abs 0.1% (=1 g/l) 0.739, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.06 This classifies the protein as unstable. Aliphatic index: 88.50 Grand average of hydropathicity (GRAVY): -0.187