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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MADGEDIQPL VCDNGTGMVK AGFAGDDAPR AVFPSIVGRP RHTGVMVGMG QKDAYVGDEA

70 80 90 100 110 120
QSKRGILTLK YPIEHGIVSN WDDMEKIWHH TFYNELRVAP EEHPVLLTEA PLNPKANREK

130 140 150 160 170 180
MTQIMFETFN VPAMYVAIQA VLSLYASGRT TGIVLDSGDG VSHTVPIYEG YALPHAILRL

190 200 210 220 230 240
DLAGRDLTDS LMKILTERGY MFTTTAEREI VRDIKEKLAY VALDYEQELE TAKSSSSVEK

250 260 270 280 290 300
NYELPDGQVI TIGAERFRCP EVLFQPSLIG MEAPGIHETT YNSIMKCDVD IRKDLYGNIV

310 320 330 340 350 360
LSGGSTMFPG IADRMSKEIT ALAPSSMKIK VVAPPERKYS VWIGGSILAS LSTFQQMWIS

370
KSEYDESGPS IVHRKCF


References and documentation are available.

Number of amino acids: 377 Molecular weight: 41735.78 Theoretical pI: 5.31
Amino acid composition: 
Ala (A) 28 7.4% Arg (R) 18 4.8% Asn (N) 9 2.4% Asp (D) 22 5.8% Cys (C) 4 1.1% Gln (Q) 10 2.7% Glu (E) 28 7.4% Gly (G) 30 8.0% His (H) 9 2.4% Ile (I) 28 7.4% Leu (L) 28 7.4% Lys (K) 20 5.3% Met (M) 16 4.2% Phe (F) 11 2.9% Pro (P) 21 5.6% Ser (S) 27 7.2% Thr (T) 22 5.8% Trp (W) 4 1.1% Tyr (Y) 15 4.0% Val (V) 27 7.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 50 Total number of positively charged residues (Arg + Lys): 38 Atomic composition: Carbon C 1855 Hydrogen H 2924 Nitrogen N 492 Oxygen O 561 Sulfur S 20 Formula: C1855H2924N492O561S20 Total number of atoms: 5852 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 44600 Abs 0.1% (=1 g/l) 1.069, assuming all pairs of Cys residues form cystines Ext. coefficient 44350 Abs 0.1% (=1 g/l) 1.063, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.39 This classifies the protein as stable. Aliphatic index: 86.13 Grand average of hydropathicity (GRAVY): -0.179