ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MADSSSSLHP LCERISHKSY VLRAVDLTIL GLLYSLLLYR ILHISENDNV WLLAFFCESC 

        70         80         90        100        110        120 
FSLVWLIFTC LKWSPAEDIP YINTLNERVH DLPSLDMFVP TADTVRESPI ITVNTVLSLL 

       130        140        150        160        170        180 
AVNYPANKLA CYVSDDGCSP LTYFSLKEAS KFVKIWAPFC KKYNVRVRAP FRYFLNPLVA 

       190        200        210        220        230        240 
TDDSVFSKDW KMMKREYVKL CRKVEDATGD SHWLDADDDF EAFSNTKPND HSTIVKVVWE 

       250        260        270        280        290        300 
NKGGVGDEKE VPHLVYISRE KRPNYLHHYK TGAMNFLLRV SGLMTNAPYT LNVDCDMYAN 

       310        320        330        340        350        360 
EPDVVRQAMC VFLQNSKNSN HCAFVQFPQK FYDSYTNELA VLQSILGRGV AGIQGPFYIG 

       370        380        390        400        410        420 
TGCFHTRRVM YGLSSDDLED NGNISQVATR EFLAEDSLVR KYGNSKELVK SVVDALQRKS 

       430        440        450        460        470        480 
NPQKSLANLI EAAQEVGHCH YEYQTSWGNL GWMYDSVAED INTSVGIHLR GWTSSFISPD 

       490        500        510        520        530        540 
PPAFIGSTPT LGLEAIVQQR RWATGAIEVL FNKQSPFMGM FHGKIKFRQR LAYFWALMCL 

       550        560        570        580        590        600 
RSIPELIYCL LPAYCLLHDS ALFPKGPCLC TIVTLVGMHC LYSLWQFMSL GFSVQSWYVV 

       610        620        630        640        650        660 
QSLWRIIATS SWLFSIQDII LKLLGISQIG FVIAKKTIPE TKSVYESKPS QGEDDVPKLN 

       670        680        690        700        710        720 
LGKFEFDSSG LFIPGTFIML VNLAALAGYL VRLQRSSCSH GGGGSGLAEA CGCILVVMLF 

       730        740        750 
LPFLKGLFEH GKYSIPLSTL SKAAFLTVLF VFFCVGK 

References and documentation are available.

Number of amino acids: 757

Molecular weight: 85200.58

Theoretical pI: 7.22

Amino acid composition: 
Ala (A)  46	  6.1%
Arg (R)  29	  3.8%
Asn (N)  31	  4.1%
Asp (D)  37	  4.9%
Cys (C)  23	  3.0%
Gln (Q)  22	  2.9%
Glu (E)  33	  4.4%
Gly (G)  46	  6.1%
His (H)  19	  2.5%
Ile (I)  40	  5.3%
Leu (L)  89	 11.8%
Lys (K)  41	  5.4%
Met (M)  17	  2.2%
Phe (F)  44	  5.8%
Pro (P)  34	  4.5%
Ser (S)  68	  9.0%
Thr (T)  33	  4.4%
Trp (W)  16	  2.1%
Tyr (Y)  31	  4.1%
Val (V)  58	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 70
Total number of positively charged residues (Arg + Lys): 70

Atomic composition:

Carbon      C	      3886
Hydrogen    H	      5974
Nitrogen    N	       992
Oxygen      O	      1083
Sulfur      S	        40

Formula: C3886H5974N992O1083S40
Total number of atoms: 11975

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   135565
Abs 0.1% (=1 g/l)   1.591, assuming all pairs of Cys residues form cystines


Ext. coefficient   134190
Abs 0.1% (=1 g/l)   1.575, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.34
This classifies the protein as unstable.



Aliphatic index: 94.76

Grand average of hydropathicity (GRAVY): 0.094