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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MADVDDFDSL SNAELRAKML AQGLPNIPVT DSSRKVLVKR LRASIGGQAS PAASPKKTNR

70 80 90 100 110 120
RETLAPAPGA PSAPAAASTP VDKLDGNKVA PATKARRTIT AAEAKEPVRR LPEEAIRRRP

130 140 150 160 170 180
DEADRLRSEE PVAARKPTTA PAAQPVQTRR TSTSSGSERK VVEPLRKPET IVEQPASSKR

190 200 210 220 230 240
ADREENYLKV NSLIVLESDE EEDEQLVQAA DLVEQEHAAR QKTTKLASSG TTTYEYKSKV

250 260 270 280 290 300
VEPPRRQVYE ATAAPVLPPS VPSARAQTTS STRSYDYASN PAPGRYSSFV RTAAQGYVTA

310 320 330 340 350 360
EAPPVASYSS SYKRTYANEL SDDTDSKEDQ YESTFARNLA RLRAERIGDR ISPYSRRTLA

370 380 390 400 410 420
SGNAGSGSLG YEPRARRSLR PNDNSVSEAF NRWLNSLEQK YHIKSKLFIV LLVLLLIGVY


YIFY


References and documentation are available.

Number of amino acids: 424 Molecular weight: 46584.10 Theoretical pI: 9.56
Amino acid composition: 
Ala (A) 55 13.0% Arg (R) 42 9.9% Asn (N) 14 3.3% Asp (D) 20 4.7% Cys (C) 0 0.0% Gln (Q) 14 3.3% Glu (E) 33 7.8% Gly (G) 15 3.5% His (H) 2 0.5% Ile (I) 12 2.8% Leu (L) 32 7.5% Lys (K) 23 5.4% Met (M) 2 0.5% Phe (F) 6 1.4% Pro (P) 33 7.8% Ser (S) 46 10.8% Thr (T) 28 6.6% Trp (W) 1 0.2% Tyr (Y) 18 4.2% Val (V) 28 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 65 Atomic composition: Carbon C 2024 Hydrogen H 3280 Nitrogen N 606 Oxygen O 651 Sulfur S 2 Formula: C2024H3280N606O651S2 Total number of atoms: 6563 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 32320 Abs 0.1% (=1 g/l) 0.694 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 68.71 This classifies the protein as unstable. Aliphatic index: 72.59 Grand average of hydropathicity (GRAVY): -0.696