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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAEASIEKTQ ILQKYLELDQ RGRIIAEYVW IDGTGNLRSK GRTLKKRITS IDQLPEWNFD

70 80 90 100 110 120
GSSTNQAPGH DSDIYLKPVA YYPDPFRRGD NIVVLAACYN NDGTPNKFNH RHEAAKLFAA

130 140 150 160 170 180
HKDEEIWFGL EQEYTLFDMY DDVYGWPKGG YPAPQGPYYC GVGAGKVYAR DMIEAHYRAC

190 200 210 220 230 240
LYAGLEISGI NAEVMPSQWE FQVGPCTGID MGDQLWMARY FLHRVAEEFG IKISFHPKPL

250 260 270 280 290 300
KGDWNGAGCH TNVSTKEMRQ PGGMKYIEQA IEKLSKRHAE HIKLYGSDND MRLTGRHETA

310 320 330 340 350 360
SMTAFSSGVA NRGSSIRIPR SVAKEGYGYF EDRRPASNID PYLVTGIMCE TVCGAIDNAD

370
MTKEFERESS


References and documentation are available.

Number of amino acids: 370 Molecular weight: 41766.00 Theoretical pI: 5.92
Amino acid composition: 
Ala (A) 30 8.1% Arg (R) 22 5.9% Asn (N) 15 4.1% Asp (D) 23 6.2% Cys (C) 7 1.9% Gln (Q) 12 3.2% Glu (E) 27 7.3% Gly (G) 35 9.5% His (H) 11 3.0% Ile (I) 24 6.5% Leu (L) 20 5.4% Lys (K) 21 5.7% Met (M) 12 3.2% Phe (F) 13 3.5% Pro (P) 18 4.9% Ser (S) 21 5.7% Thr (T) 16 4.3% Trp (W) 7 1.9% Tyr (Y) 21 5.7% Val (V) 15 4.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 50 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1851 Hydrogen H 2821 Nitrogen N 513 Oxygen O 556 Sulfur S 19 Formula: C1851H2821N513O556S19 Total number of atoms: 5760 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 70165 Abs 0.1% (=1 g/l) 1.680, assuming all pairs of Cys residues form cystines Ext. coefficient 69790 Abs 0.1% (=1 g/l) 1.671, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.35 This classifies the protein as unstable. Aliphatic index: 66.24 Grand average of hydropathicity (GRAVY): -0.574