ProtParam
User-provided sequence:
10 20 30 40 50 60
MAENVVEPGP PSAKRPKLSS PALSASASDG TDFGSLFDLE HDLPDELINS TELGLTNGGD
70 80 90 100 110 120
ISQLQTSLGI VQDAASKHKQ LSELLRSGSS PNLNMGVGGP GQVMASQAQQ NSPGLSLINS
130 140 150 160 170 180
MVKSPMAQTG LTSPNMGMGS SGPNQGPTQS TAGMMNSPVN QPAMGMNTGM NAGMNPGMLA
190 200 210 220 230 240
AGNGQGIMPN QVMNGSIGAG RGRPNMQYPN AGMGNAGSLL TEPLQQGSPQ MGGQPGLRGP
250 260 270 280 290 300
QSHKMGMMSN PTPYGSPYTQ NSGQQIGASG LGLQIQTKTV LPNNLSPFAM DKKAVTGGGM
310 320 330 340 350
PNMGQQPTPS VQQPGLVNPV APGMGSGAHT ADPEKRKLIQ QQLVLLLHAH KCQ
References and
documentation are available.
Number of amino acids: 353
Molecular weight: 36048.76
Theoretical pI: 7.89
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 18
Atomic composition:
Carbon C 1522
Hydrogen H 2476
Nitrogen N 454
Oxygen O 503
Sulfur S 27
Formula: C
1522H
2476N
454O
503S
27
Total number of atoms: 4982
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 0.124, assuming all pairs of Cys residues form cystines
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 0.124, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 50.72
This classifies the protein as unstable.
Aliphatic index: 63.88
Grand average of hydropathicity (GRAVY): -0.437