ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAEPAQETPC FSMEKAERAF LDGNFEEALK HFFVCIRMLP VERRGVYEDQ FAAALHGWIA 

        70         80         90        100        110        120 
LDHNNASRAV CLYPQIKELF PETIRTKIAL IRAVQGTEQS KWLLNCLPIC KDSMDLATKP 

       130        140        150        160        170        180 
EDLVALRIAR VNLTTIPFPQ WHIRMINDVK RNEAFAKALN DTIKSRITVV FDIGSGTGIL 

       190        200        210        220        230        240 
SAIAARKTNL VTALEENMCL TMISKEVLKR NGVESRVNVH AKNSTYFETC EKADIVVSET 

       250        260        270        280        290        300 
LDCCVFGEKI VETFLDAHVR FSHDRTIFIP HQATVYVRLF SCREIFDIHC QDYGGVRYRS 

       310        320        330        340        350        360 
EYVKIGESDA EQPYWCASAA DYSQFELLSG SVAMHSVDFS SIANLKDSLA NSNSFKIRPA 

       370        380        390        400        410        420 
KDGVAHGFSV HFTSDLTGHG DNIIDSSKSR AWDLGIIPFK EPCLVKCDKE YEGSWKLLNN 

       430        440        450        460        470        480 
RLDVYNDFYD ENLQKHEDSL RYETASLDQL QKIRDDSYFK AMMGEIDPIE LPFTRDISSS 

       490        500        510        520        530        540 
IPAQCVLNTV ESQTPIRHLI TNFCRYDGTL DQETFFRIEE FVGFRDHVQK IVPTKFRILG 

       550        560        570        580        590        600 
HLFYSDRVHF DARPDPSAHC QVDLSTVRSF NLREMRDIRL TQREDIVMAS KEFVLYDFNI 

       610        620        630        640        650        660 
SAEKFRQDTY ITVTQDVTVQ PTRPIADGVI YEFEILGIRN TKLRPVAAFL FPERVNTNPD 

       670        680 
MTVVFDLHLG EMLISLKDLP 

References and documentation are available.

Number of amino acids: 680

Molecular weight: 77764.67

Theoretical pI: 5.58

Amino acid composition: 
Ala (A)  47	  6.9%
Arg (R)  44	  6.5%
Asn (N)  28	  4.1%
Asp (D)  50	  7.4%
Cys (C)  17	  2.5%
Gln (Q)  22	  3.2%
Glu (E)  47	  6.9%
Gly (G)  26	  3.8%
His (H)  20	  2.9%
Ile (I)  49	  7.2%
Leu (L)  56	  8.2%
Lys (K)  34	  5.0%
Met (M)  14	  2.1%
Phe (F)  42	  6.2%
Pro (P)  27	  4.0%
Ser (S)  45	  6.6%
Thr (T)  39	  5.7%
Trp (W)   6	  0.9%
Tyr (Y)  19	  2.8%
Val (V)  48	  7.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 97
Total number of positively charged residues (Arg + Lys): 78

Atomic composition:

Carbon      C	      3470
Hydrogen    H	      5408
Nitrogen    N	       942
Oxygen      O	      1028
Sulfur      S	        31

Formula: C3470H5408N942O1028S31
Total number of atoms: 10879

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    62310
Abs 0.1% (=1 g/l)   0.801, assuming all pairs of Cys residues form cystines


Ext. coefficient    61310
Abs 0.1% (=1 g/l)   0.788, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.67
This classifies the protein as stable.



Aliphatic index: 87.60

Grand average of hydropathicity (GRAVY): -0.220