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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAESDSGEST SSVSSFISSS SSSRLSEFVD AKTELQDIYH DLSNYLSNFL TILEETVLLK

70 80 90 100 110 120
DRQMLEHLCA FSSRVEAIAK VLSRDRMKVA FFGRTSNGKS AVINALLHEK ILPSAMGHTT

130 140 150 160 170 180
SCFCQVQANG SNETEHVKVE QEDEHMELSA LSQLASAHSP GALKPSTLLQ VNMAKNRCSI

190 200 210 220 230 240
LDYDVVLMDT PGVDVTAQLD DCLDSYCMDA DVFILVLNAE STVSRVERQF FKDVASKLSR

250 260 270 280 290 300
PNLFILNNRW DKASSLEPEM EQKVKDQHME RCVNLLVDEL GVYSTAQEAW ERIYHVSALE

310 320 330 340 350 360
ALHIRNGQIT NPSGQTQQRY QEFLRFENDF SNCLAVSALK TKFGPHLLSA QKILNQLKST

370 380 390 400 410 420
LICPFIEKVS RLIDENKERR ANLNAEIEDW LILMQEDREA LQYCFEELTE MTQRVGRCVL

430 440 450 460 470 480
NDQIKTLIPS SVLSFSQPFH PEFPAQIGQY QRSLCAHLDK LLEDRVLQCL SIPLQRKILD

490 500 510 520 530 540
IEKEIGLPIA ENSCDWQLIY GLDCQSYMSD FQPDLRFRFS LGFTALWHRL EGNLPLHASP

550 560 570 580 590 600
FRIQKLQNGH KKCSPLPPLV NGNHWQMLES LVKSKGSLGT VLLSAMAIRS FNWPIVLILG

610 620 630 640 650 660
GLVGSFYIYE YAAWTTAAQE RSFKSQYARL LQQRLRSDVQ QTVSGFELQL RQHLATVRNC

670 680 690 700 710
WEAQSNETLN DLNVRTAELT KQIQSMEVLQ LSLKKFRDKG QLLASRLGDF QETYLTKS


References and documentation are available.

Number of amino acids: 718 Molecular weight: 81565.01 Theoretical pI: 5.78
Amino acid composition: 
Ala (A) 46 6.4% Arg (R) 39 5.4% Asn (N) 32 4.5% Asp (D) 36 5.0% Cys (C) 17 2.4% Gln (Q) 49 6.8% Glu (E) 52 7.2% Gly (G) 27 3.8% His (H) 18 2.5% Ile (I) 33 4.6% Leu (L) 96 13.4% Lys (K) 35 4.9% Met (M) 16 2.2% Phe (F) 31 4.3% Pro (P) 22 3.1% Ser (S) 72 10.0% Thr (T) 31 4.3% Trp (W) 9 1.3% Tyr (Y) 16 2.2% Val (V) 41 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 88 Total number of positively charged residues (Arg + Lys): 74 Atomic composition: Carbon C 3603 Hydrogen H 5716 Nitrogen N 996 Oxygen O 1095 Sulfur S 33 Formula: C3603H5716N996O1095S33 Total number of atoms: 11443 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 74340 Abs 0.1% (=1 g/l) 0.911, assuming all pairs of Cys residues form cystines Ext. coefficient 73340 Abs 0.1% (=1 g/l) 0.899, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.51 This classifies the protein as unstable. Aliphatic index: 93.04 Grand average of hydropathicity (GRAVY): -0.261