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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAETQGKVIT CKAAVVWGPK VPLVIQEICV DPPQKMEVRV KILYSSICHT DLGCWNGTNE

70 80 90 100 110 120
AERAFPRILG HEAVGIVESV GEGVKDVKEG DYVIPTFNGE CGECKVCKRE ESNLCERYHV

130 140 150 160 170 180
DPMKRVMVND GGTRFSTTIN KDGGSSQSQP IYHFLNTSTF TEYTVLDSAC VVKIDPNSPL

190 200 210 220 230 240
KQMSLLSCGV STGVGAAWNI ANVKEGKSTA VFGLGSVGLA VAEGARARGA SRIIGVDANA

250 260 270 280 290 300
SKFEKGKLMG VTDFINPKDL TKPVHQMIRE ITGGGVDYSF ECTGNVDVLR EAFLSTHVGW

310 320 330 340 350 360
GSTVLVGIYP TPRTLPLHPM ELFDGRRITG SVFGGFKPKS QLPNFAQQCM KGVVKLEPFI

370 380 390
TNELPFEKIN DAFQLLRDGK SLRCILQISK LLKR


References and documentation are available.

Number of amino acids: 394 Molecular weight: 42907.50 Theoretical pI: 8.34
Amino acid composition: 
Ala (A) 21 5.3% Arg (R) 18 4.6% Asn (N) 16 4.1% Asp (D) 17 4.3% Cys (C) 13 3.3% Gln (Q) 12 3.0% Glu (E) 25 6.3% Gly (G) 40 10.2% His (H) 7 1.8% Ile (I) 23 5.8% Leu (L) 29 7.4% Lys (K) 28 7.1% Met (M) 9 2.3% Phe (F) 17 4.3% Pro (P) 20 5.1% Ser (S) 25 6.3% Thr (T) 24 6.1% Trp (W) 4 1.0% Tyr (Y) 7 1.8% Val (V) 39 9.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 42 Total number of positively charged residues (Arg + Lys): 46 Atomic composition: Carbon C 1900 Hydrogen H 3038 Nitrogen N 522 Oxygen O 563 Sulfur S 22 Formula: C1900H3038N522O563S22 Total number of atoms: 6045 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 33180 Abs 0.1% (=1 g/l) 0.773, assuming all pairs of Cys residues form cystines Ext. coefficient 32430 Abs 0.1% (=1 g/l) 0.756, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.44 This classifies the protein as stable. Aliphatic index: 85.51 Grand average of hydropathicity (GRAVY): -0.108