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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAETSNDPFL SYVLSSKQLT NLNRLRRKAV TKQLGSSDDN KVSEEFLRYQ HTYQREAFEY

70 80 90 100 110 120
LQTKHDAHKI MESQYEQYQS SSKTRRYSID LDSVDAVDTE SQTEYPNEEF IDRNEDSEAV

130 140 150 160 170 180
MELRKRLLGK GQNKGLGYET TKSVDRQIED QDTLQQDLIQ DMSKLVGSLK QGAVAFQSAL

190 200 210 220 230 240
DEDKQVLGAA EIGIQVASQG LMDVSGKLRK YDKSKLSYLF YITVFIFMIL GLVFTFIIIQ


LFPAL


References and documentation are available.

Number of amino acids: 245 Molecular weight: 28106.66 Theoretical pI: 5.15
Amino acid composition: 
Ala (A) 13 5.3% Arg (R) 12 4.9% Asn (N) 7 2.9% Asp (D) 19 7.8% Cys (C) 0 0.0% Gln (Q) 21 8.6% Glu (E) 18 7.3% Gly (G) 12 4.9% His (H) 3 1.2% Ile (I) 13 5.3% Leu (L) 27 11.0% Lys (K) 18 7.3% Met (M) 6 2.4% Phe (F) 11 4.5% Pro (P) 3 1.2% Ser (S) 23 9.4% Thr (T) 13 5.3% Trp (W) 0 0.0% Tyr (Y) 12 4.9% Val (V) 14 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 37 Total number of positively charged residues (Arg + Lys): 30 Atomic composition: Carbon C 1243 Hydrogen H 1969 Nitrogen N 333 Oxygen O 396 Sulfur S 6 Formula: C1243H1969N333O396S6 Total number of atoms: 3947 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 17880 Abs 0.1% (=1 g/l) 0.636 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.83 This classifies the protein as unstable. Aliphatic index: 85.55 Grand average of hydropathicity (GRAVY): -0.524