ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAEVEKPTAA TPPTDIPQAT AAPASEAPVA VTPTADTTVD VEPGTSPTQE PNSNSHPHDS 

        70         80         90        100        110        120 
EYDTASDLEG GEDYDDEESA SGSASGSGSE EESETDDEDD EVGSETDDGE GEQAMDRSVA 

       130        140        150        160        170        180 
DSEAQKKVDE DRSNPQYIPK RGTFYEHDDR TAETEGEILI EPENGAGQAA AEPNGELNGL 

       190        200        210        220        230        240 
AAAGATPTGQ TPQISQASKT MRKWQPASGG DRWSHDRFEA TEQAPKSRAE LLQTYGYDIR 

       250        260        270        280        290        300 
NEDAPPRARR RRRYTRGPSK YSRNWEDEQA YLKASNKERK PPRPQDFPAL NERKPRGPRT 

       310        320        330        340        350        360 
SSSREEKENR RSVAAEGLVP EKQQPLASSS NPHRSQERER ERERERERDR EPKNRNFGRM 

       370        380        390        400        410        420 
NGGPGRQNGM EFKKNNRGQQ LRERERGPDQ LDNRNQKPST PRSNQQQQPQ QQPHHQQQPQ 

       430        440        450        460        470        480 
QQRQPSQPQQ SPQTPLSTSN LSQRLQQVQQ RNDPSHVGSV QMHSLASQNQ APQQQQQQPL 

       490        500        510        520        530        540 
HQEQRNAPKR YSSLRRSQQE ASQHLAEQQQ QQMQQQLHLQ QQQQQQQSQI MIQDPHVLMQ 

       550        560        570        580        590        600 
IAYQQQELQA QLQTMQLGPP TAAGAVPTPP KPHAPPAAAY PQAQAAPYYV TGTEPVPVPV 

       610        620        630        640        650        660 
PQAPYVNPAS AAYLPTTPAA VAYAQAGPPV VTQPTPPPAQ APPATQPAQP YQNYNTVGGT 

       670        680        690        700        710        720 
TYFVPPAQTT SRPSALPQRR PTNAIPILPP SEKHKVKGGA KEEGISDNID HIIDNMFVQR 

       730        740        750        760 
PSAFQATGEG ATPGGGTKEE AAATPPAAEQ NLQPVPATGQ E 

References and documentation are available.

Number of amino acids: 761

Molecular weight: 83669.73

Theoretical pI: 5.35

Amino acid composition: 
Ala (A)  81	 10.6%
Arg (R)  53	  7.0%
Asn (N)  32	  4.2%
Asp (D)  35	  4.6%
Cys (C)   0	  0.0%
Gln (Q) 101	 13.3%
Glu (E)  65	  8.5%
Gly (G)  46	  6.0%
His (H)  16	  2.1%
Ile (I)  15	  2.0%
Leu (L)  29	  3.8%
Lys (K)  25	  3.3%
Met (M)  11	  1.4%
Phe (F)   8	  1.1%
Pro (P)  90	 11.8%
Ser (S)  55	  7.2%
Thr (T)  48	  6.3%
Trp (W)   3	  0.4%
Tyr (Y)  20	  2.6%
Val (V)  28	  3.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 100
Total number of positively charged residues (Arg + Lys): 78

Atomic composition:

Carbon      C	      3548
Hydrogen    H	      5581
Nitrogen    N	      1113
Oxygen      O	      1218
Sulfur      S	        11

Formula: C3548H5581N1113O1218S11
Total number of atoms: 11471

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46300
Abs 0.1% (=1 g/l)   0.553

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 72.12
This classifies the protein as unstable.



Aliphatic index: 43.86

Grand average of hydropathicity (GRAVY): -1.297