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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAEVPHHNIP AVDMLNATSR LQLEAQELRN NKPNWGSYFR SQMIQEDDYN FITSFENAKS

70 80 90 100 110 120
KEERDQVLAA NNANGQAAKT MANLITQVAK DQNVRYVLTL FDDMLQEDKS RVELFHSAAA

130 140 150 160 170 180
RQKRTVWSQY LGILQRQDNF IVNQMSSIIA KLACFGTTRM EGQDLQYYFS FLKEQLKNST

190 200 210 220 230 240
TNDYMNTTAR CLQMMLRHDE YRHEFVDSDG VQTLVTALNG KTNFQLQYQL IFAVWCLTFN

250 260 270 280 290 300
ADIARKAPSL GLIQALGDIL SESTKEKVIR IILASFVNIL SKVDEREVKR EAALQMVQCK

310 320 330 340 350 360
TLKTLELMDA KKYDDPDLED DVKFLTEELT LSVHDLSSYD EYYSEVRSGR LQWSPVHKSE

370 380 390 400 410 420
KFWRENASKF NDKQFEVVKI LIKLLESSHD PLILCVASHD IGEYVRHYPR GKTVVEQYQG

430 440 450 460 470
KAAVMRLLTA EDPNVRYHAL LAVQKLMVHN WEYLGKQLDS DVQTDTVAVK


References and documentation are available.

Number of amino acids: 470 Molecular weight: 54212.65 Theoretical pI: 5.90
Amino acid composition: 
Ala (A) 36 7.7% Arg (R) 24 5.1% Asn (N) 25 5.3% Asp (D) 32 6.8% Cys (C) 5 1.1% Gln (Q) 32 6.8% Glu (E) 32 6.8% Gly (G) 14 3.0% His (H) 12 2.6% Ile (I) 20 4.3% Leu (L) 51 10.9% Lys (K) 32 6.8% Met (M) 14 3.0% Phe (F) 18 3.8% Pro (P) 9 1.9% Ser (S) 30 6.4% Thr (T) 25 5.3% Trp (W) 6 1.3% Tyr (Y) 18 3.8% Val (V) 35 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 64 Total number of positively charged residues (Arg + Lys): 56 Atomic composition: Carbon C 2403 Hydrogen H 3789 Nitrogen N 661 Oxygen O 729 Sulfur S 19 Formula: C2403H3789N661O729S19 Total number of atoms: 7601 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 60070 Abs 0.1% (=1 g/l) 1.108, assuming all pairs of Cys residues form cystines Ext. coefficient 59820 Abs 0.1% (=1 g/l) 1.103, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.01 This classifies the protein as unstable. Aliphatic index: 88.17 Grand average of hydropathicity (GRAVY): -0.425