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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAFSMLFTGH AECGGYTKEN VARCWTVETG ILLDTELPNE IPENDYIKYF APDFSLKIPG

70 80 90 100 110 120
GHIENLNTKS YISSIKVQIL ENLRYIQHAP SVQMQEVPPD FYIPDFDEDE QNPDVRVDQR

130 140
SRDKQIQRDD EYFDGDNDND AS


References and documentation are available.

Number of amino acids: 142 Molecular weight: 16384.03 Theoretical pI: 4.29
Amino acid composition: 
Ala (A) 6 4.2% Arg (R) 6 4.2% Asn (N) 9 6.3% Asp (D) 16 11.3% Cys (C) 2 1.4% Gln (Q) 8 5.6% Glu (E) 12 8.5% Gly (G) 7 4.9% His (H) 3 2.1% Ile (I) 11 7.7% Leu (L) 8 5.6% Lys (K) 6 4.2% Met (M) 3 2.1% Phe (F) 7 4.9% Pro (P) 9 6.3% Ser (S) 8 5.6% Thr (T) 6 4.2% Trp (W) 1 0.7% Tyr (Y) 7 4.9% Val (V) 7 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 28 Total number of positively charged residues (Arg + Lys): 12 Atomic composition: Carbon C 722 Hydrogen H 1090 Nitrogen N 190 Oxygen O 237 Sulfur S 5 Formula: C722H1090N190O237S5 Total number of atoms: 2244 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 16055 Abs 0.1% (=1 g/l) 0.980, assuming all pairs of Cys residues form cystines Ext. coefficient 15930 Abs 0.1% (=1 g/l) 0.972, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.27 This classifies the protein as stable. Aliphatic index: 70.70 Grand average of hydropathicity (GRAVY): -0.739