ProtParam
User-provided sequence:
10 20 30 40 50 60
MAGDSDNVSL PKATVQKMIS EILDQDLMFT KDAREIIINS GIEFIMILSS MASEMADNEA
70 80 90 100 110 120
KKTIAPEHVI KALEELEYNE FIPFLEEILL NFKGSQKVKE TRDSKFKKSG LSEEELLRQQ
130 140
EELFRQSRSR LHHNSVSDPV KSEDSS
References and
documentation are available.
Number of amino acids: 146
Molecular weight: 16649.87
Theoretical pI: 4.89
Total number of negatively charged residues (Asp + Glu): 28
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 727
Hydrogen H 1177
Nitrogen N 195
Oxygen O 238
Sulfur S 6
Formula: C
727H
1177N
195O
238S
6
Total number of atoms: 2343
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.089
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 68.86
This classifies the protein as unstable.
Aliphatic index: 86.85
Grand average of hydropathicity (GRAVY): -0.521