ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAGGAVVSTG AGKDYPGKLT LFVFFTCVVA ATGGLIFGYD IGISGGVTSM DPFLRKFFPE 

        70         80         90        100        110        120 
VYRKKQMADK NNQYCKYDNQ LLQTFTSSLY LAALVSSFFA ATVTRVLGRK WSMFAGGLTF 

       130        140        150        160        170        180 
LIGAALNGAA ENVAMLIVGR ILLGVGVGFA NQSVPVYLSE MAPARLRGML NIGFQLMITI 

       190        200        210        220        230        240 
GILAAELINY GTAKIKAGWG WRVSLALAAV PAAIITLGSL FLPDTPNSLI DRGHPEAAER 

       250        260        270        280        290        300 
MLRRIRGSDV DVSEEYADLV AASEESKLVQ HPWRNILRRK YRAQLTMAIC IPFFQQLTGI 

       310        320        330        340        350        360 
NVIMFYAPVL FDTLGFKSDA SLMSAVITGL VNVFATLVSI FTVDRLGRRK LFLQGGAQMV 

       370        380        390        400        410        420 
VCQVVVGTLI AVKFGTSGIG DIPKGYAAVV VLFICMYVAG FAWSWGPLGW LVPSEIFPLE 

       430        440        450        460        470        480 
IRPAGQSINV SVNMLFTFVI AQAFLTMLCH MKFGLFYFFA GWVVIMTVFI ALFLPETKNV 

       490        500        510 
PIEEMVLVWK SHWFWRRFIG DHDVHVGANH VSNNKLQP 

References and documentation are available.

Number of amino acids: 518

Molecular weight: 56764.93

Theoretical pI: 9.39

Amino acid composition: 
Ala (A)  51	  9.8%
Arg (R)  23	  4.4%
Asn (N)  18	  3.5%
Asp (D)  16	  3.1%
Cys (C)   6	  1.2%
Gln (Q)  16	  3.1%
Glu (E)  15	  2.9%
Gly (G)  48	  9.3%
His (H)   7	  1.4%
Ile (I)  35	  6.8%
Leu (L)  55	 10.6%
Lys (K)  20	  3.9%
Met (M)  19	  3.7%
Phe (F)  38	  7.3%
Pro (P)  20	  3.9%
Ser (S)  28	  5.4%
Thr (T)  26	  5.0%
Trp (W)  11	  2.1%
Tyr (Y)  14	  2.7%
Val (V)  52	 10.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      2630
Hydrogen    H	      4086
Nitrogen    N	       666
Oxygen      O	       683
Sulfur      S	        25

Formula: C2630H4086N666O683S25
Total number of atoms: 8090

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    81735
Abs 0.1% (=1 g/l)   1.440, assuming all pairs of Cys residues form cystines


Ext. coefficient    81360
Abs 0.1% (=1 g/l)   1.433, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.77
This classifies the protein as stable.



Aliphatic index: 106.72

Grand average of hydropathicity (GRAVY): 0.546