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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAGIVTEPWS VAENGNPSIT AKGSSRELRL GRTAHNMSSS SLRKKSDLRV IQKVPYKGLK

70 80 90 100 110 120
DFLSNLQEVI LGTKLAILFP AIPAAIICTY CGVSQPWIFG LSLLGLTPLA ERVSFLTEQL

130 140 150 160 170 180
AFYTGPTLGG LLNATCGNAT ELIIAILALT NNKVAVVKYS LLGSILSNLL LVLGTSLFCG

190 200 210 220 230 240
GIANIRREQR FDRKQADVNF FLLLLGFLCH LLPLLVGYLK NGEASAAVLS DMQLSISRGF

250 260 270 280 290 300
SIVMLISYIA YLVFQLWTHR QLFDAQEQED EYDDDVEQET AVISFWSGFA WLVGMTLVIA

310 320 330 340 350 360
LLSEYVVATI EEASDKWNLS VSFISIILLP IVGNAAEHAG AVIFAFKNKL DISLGVALGS

370 380 390 400 410 420
ATQIGLFVVP LTIIVAWILG INMDLNFGPL ETGCLAVSII ITAFTLQDGS SHYMKGLVLL

430 440 450 460
LCYFIIAICF FVDKLPQKQN AIHLGHQAMN NVVTATGGGV FSS


References and documentation are available.

Number of amino acids: 463 Molecular weight: 50176.79 Theoretical pI: 5.84
Amino acid composition: 
Ala (A) 41 8.9% Arg (R) 12 2.6% Asn (N) 20 4.3% Asp (D) 15 3.2% Cys (C) 8 1.7% Gln (Q) 17 3.7% Glu (E) 19 4.1% Gly (G) 37 8.0% His (H) 7 1.5% Ile (I) 40 8.6% Leu (L) 70 15.1% Lys (K) 17 3.7% Met (M) 8 1.7% Phe (F) 25 5.4% Pro (P) 13 2.8% Ser (S) 37 8.0% Thr (T) 24 5.2% Trp (W) 7 1.5% Tyr (Y) 11 2.4% Val (V) 35 7.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 34 Total number of positively charged residues (Arg + Lys): 29 Atomic composition: Carbon C 2305 Hydrogen H 3654 Nitrogen N 574 Oxygen O 641 Sulfur S 16 Formula: C2305H3654N574O641S16 Total number of atoms: 7190 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 55390 Abs 0.1% (=1 g/l) 1.104, assuming all pairs of Cys residues form cystines Ext. coefficient 54890 Abs 0.1% (=1 g/l) 1.094, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.65 This classifies the protein as stable. Aliphatic index: 123.43 Grand average of hydropathicity (GRAVY): 0.601