ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAGPRNVRTL HGNGGRNNDV MGPKEFWLNI PPITRTLFTL AIVMTIVGRL NLINPWYFIY 

        70         80         90        100        110        120 
VWNLTFKKVQ IWRLLTSCVM LSSRAMPALM ELYSIYDRSS QLERGHFGPG LSNRRGPMVT 

       130        140        150        160        170        180 
VDYAYYLCFC ILAITTATTI IYGSYYPVVL TSGFISCITY TWSIDNANVQ IMFYGLIPVW 

       190        200        210        220        230        240 
GKYFPLIQLF ISFVFNEGDF VISLIGFTTG YLYTCLDTHT LGPIWGMISR KADPTYGISP 

       250        260        270        280        290        300 
NGKFSTPWWF TSLYARITGA HNETATFNNN FANVPSSQRE TRTFSGRGQR LGTAPATLSQ 

       310        320        330        340 
TSGTDSGRAS GSQLRSGPSN LNQFQGRGQR VGQTNSPSDS Q 

References and documentation are available.

Number of amino acids: 341

Molecular weight: 38130.62

Theoretical pI: 9.63

Amino acid composition: 
Ala (A)  16	  4.7%
Arg (R)  21	  6.2%
Asn (N)  21	  6.2%
Asp (D)   9	  2.6%
Cys (C)   5	  1.5%
Gln (Q)  13	  3.8%
Glu (E)   6	  1.8%
Gly (G)  32	  9.4%
His (H)   4	  1.2%
Ile (I)  25	  7.3%
Leu (L)  29	  8.5%
Lys (K)   6	  1.8%
Met (M)   9	  2.6%
Phe (F)  20	  5.9%
Pro (P)  19	  5.6%
Ser (S)  30	  8.8%
Thr (T)  33	  9.7%
Trp (W)   9	  2.6%
Tyr (Y)  17	  5.0%
Val (V)  17	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 15
Total number of positively charged residues (Arg + Lys): 27

Atomic composition:

Carbon      C	      1731
Hydrogen    H	      2637
Nitrogen    N	       461
Oxygen      O	       486
Sulfur      S	        14

Formula: C1731H2637N461O486S14
Total number of atoms: 5329

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    75080
Abs 0.1% (=1 g/l)   1.969, assuming all pairs of Cys residues form cystines


Ext. coefficient    74830
Abs 0.1% (=1 g/l)   1.962, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.31
This classifies the protein as stable.



Aliphatic index: 80.91

Grand average of hydropathicity (GRAVY): -0.042