ProtParam
User-provided sequence:
10 20 30 40 50 60
MAIETILVIN KSGGLIYQRN FTNDEQKLNS NEYLILASTL HGVFAIASQL TPKALQLTQQ
70 80 90 100 110 120
TNIENTIPYI PYVGMSSNRS DTRNGGGNNN KHTNNEKLGS FKGDDFFKEP FTNWNKSGLR
130 140 150 160 170 180
QLCTDQFTMF IYQTLTGLKF VAISSSVMPQ RQPTIATTDK PDRPKSTSNL AIQIADNFLR
190 200 210
KVYCLYSDYV MKDPSYSMEM PIRSNLFDEK VKKMVENLQ
References and
documentation are available.
Number of amino acids: 219
Molecular weight: 24863.29
Theoretical pI: 8.95
Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 24
Atomic composition:
Carbon C 1101
Hydrogen H 1737
Nitrogen N 297
Oxygen O 338
Sulfur S 10
Formula: C
1101H
1737N
297O
338S
10
Total number of atoms: 3483
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 19035
Abs 0.1% (=1 g/l) 0.766, assuming all pairs of Cys residues form cystines
Ext. coefficient 18910
Abs 0.1% (=1 g/l) 0.761, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 40.81
This classifies the protein as unstable.
Aliphatic index: 76.58
Grand average of hydropathicity (GRAVY): -0.482