ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAIETILVIN KSGGLIYQRN FTNDEQKLNS NEYLILASTL HGVFAIASQL TPKALQLTQQ 

        70         80         90        100        110        120 
TNIENTIPYI PYVGMSSNRS DTRNGGGNNN KHTNNEKLGS FKGDDFFKEP FTNWNKSGLR 

       130        140        150        160        170        180 
QLCTDQFTMF IYQTLTGLKF VAISSSVMPQ RQPTIATTDK PDRPKSTSNL AIQIADNFLR 

       190        200        210 
KVYCLYSDYV MKDPSYSMEM PIRSNLFDEK VKKMVENLQ 

References and documentation are available.

Number of amino acids: 219

Molecular weight: 24863.29

Theoretical pI: 8.95

Amino acid composition: 
Ala (A)   9	  4.1%
Arg (R)   8	  3.7%
Asn (N)  20	  9.1%
Asp (D)  11	  5.0%
Cys (C)   2	  0.9%
Gln (Q)  13	  5.9%
Glu (E)   9	  4.1%
Gly (G)  11	  5.0%
His (H)   2	  0.9%
Ile (I)  15	  6.8%
Leu (L)  19	  8.7%
Lys (K)  16	  7.3%
Met (M)   8	  3.7%
Phe (F)  11	  5.0%
Pro (P)  10	  4.6%
Ser (S)  18	  8.2%
Thr (T)  18	  8.2%
Trp (W)   1	  0.5%
Tyr (Y)   9	  4.1%
Val (V)   9	  4.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 24

Atomic composition:

Carbon      C	      1101
Hydrogen    H	      1737
Nitrogen    N	       297
Oxygen      O	       338
Sulfur      S	        10

Formula: C1101H1737N297O338S10
Total number of atoms: 3483

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    19035
Abs 0.1% (=1 g/l)   0.766, assuming all pairs of Cys residues form cystines


Ext. coefficient    18910
Abs 0.1% (=1 g/l)   0.761, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.81
This classifies the protein as unstable.



Aliphatic index: 76.58

Grand average of hydropathicity (GRAVY): -0.482