ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAILYALVAR GTVVLSEFTA TSTNASTIAK QILEKVPGDN DSNVSYSQDR YVFHVKRTDG 

        70         80         90        100        110        120 
LTVLCMAEET AGRRIPFAFL EDIHQRFVRT YGRAVHTALA YAMNEEFSRV LSQQIDYYSN 

       130        140        150        160        170        180 
DPNADRINRI KGEMNQVRGV MIENIDKVLD RGERLELLVD KTANMQGNTF RFRKQARRFR 

       190        200        210 
SNVWWRNCKL TVLLILLLLV IIYIAVAFLC HGPTLPSCI 

References and documentation are available.

Number of amino acids: 219

Molecular weight: 25038.94

Theoretical pI: 9.25

Amino acid composition: 
Ala (A)  18	  8.2%
Arg (R)  20	  9.1%
Asn (N)  13	  5.9%
Asp (D)  11	  5.0%
Cys (C)   4	  1.8%
Gln (Q)   8	  3.7%
Glu (E)  11	  5.0%
Gly (G)  10	  4.6%
His (H)   4	  1.8%
Ile (I)  15	  6.8%
Leu (L)  22	 10.0%
Lys (K)   8	  3.7%
Met (M)   6	  2.7%
Phe (F)  10	  4.6%
Pro (P)   5	  2.3%
Ser (S)  11	  5.0%
Thr (T)  14	  6.4%
Trp (W)   2	  0.9%
Tyr (Y)   8	  3.7%
Val (V)  19	  8.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 22
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	      1114
Hydrogen    H	      1782
Nitrogen    N	       318
Oxygen      O	       318
Sulfur      S	        10

Formula: C1114H1782N318O318S10
Total number of atoms: 3542

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    23170
Abs 0.1% (=1 g/l)   0.925, assuming all pairs of Cys residues form cystines


Ext. coefficient    22920
Abs 0.1% (=1 g/l)   0.915, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.54
This classifies the protein as stable.



Aliphatic index: 99.27

Grand average of hydropathicity (GRAVY): -0.067