ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAKGFKLKEL LSHQKEIEKA EKLENDLKKK KSQELKKEEP TIVTASNLKK LEKKEKKADV 

        70         80         90        100        110        120 
KKEVAADTEE YQSQALSKKE KRKLKKELKK MQEQDATEAQ KHMSGDEDES GDDREEEEEE 

       130        140        150        160        170        180 
EEEEEGRLDL EKLAKSDSES EDDSESENDS EEDEDVVAKE ESEEKEEQEE EQDVPLSDVE 

       190        200        210        220        230        240 
FDSDADVVPH HKLTVNNTKA MKHALERVQL PWKKHSFQEH QSVTSETNTD EHIKDIYDDT 

       250        260        270        280        290        300 
ERELAFYKQS LDAVLVARDE LKRLKVPFKR PLDYFAEMVK SDEHMDKIKG KLIEEASDKK 

       310        320        330        340        350        360 
AREEARRQRQ LKKFGKQVQN ATLQKRQLEK RETLEKIKSL KNKRKHNEID HSEFNVGVEE 

       370        380        390        400        410        420 
EVEGKRFDRG RPNGKRAAKN AKYGQGGMKR FKRKNDATSS ADVSGFSSRK MKGKTNRPGK 


SRRARRF 

References and documentation are available.

Number of amino acids: 427

Molecular weight: 49734.36

Theoretical pI: 6.05

Amino acid composition: 
Ala (A)  28	  6.6%
Arg (R)  27	  6.3%
Asn (N)  14	  3.3%
Asp (D)  34	  8.0%
Cys (C)   0	  0.0%
Gln (Q)  20	  4.7%
Glu (E)  70	 16.4%
Gly (G)  16	  3.7%
His (H)  11	  2.6%
Ile (I)   8	  1.9%
Leu (L)  30	  7.0%
Lys (K)  70	 16.4%
Met (M)   8	  1.9%
Phe (F)  12	  2.8%
Pro (P)   8	  1.9%
Ser (S)  30	  7.0%
Thr (T)  14	  3.3%
Trp (W)   1	  0.2%
Tyr (Y)   5	  1.2%
Val (V)  21	  4.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 104
Total number of positively charged residues (Arg + Lys): 97

Atomic composition:

Carbon      C	      2129
Hydrogen    H	      3481
Nitrogen    N	       635
Oxygen      O	       719
Sulfur      S	         8

Formula: C2129H3481N635O719S8
Total number of atoms: 6972

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    12950
Abs 0.1% (=1 g/l)   0.260

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 63.23
This classifies the protein as unstable.



Aliphatic index: 55.53

Grand average of hydropathicity (GRAVY): -1.489