ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAKKVVALIK LALPAGKANP APPVGPALGQ HGVNIMAFCK EYNAKTADKP GMIIPVEISV 

        70         80         90        100        110        120 
FEDRSFTFIL KTPPASVLIR KAAGVEKGSS EPNKNKVASI TREQLREIAQ TKLPDLNAND 

       130        140 
IDAAMNIIEG TARNMGITVN S 

References and documentation are available.

Number of amino acids: 141

Molecular weight: 14977.50

Theoretical pI: 9.48

Amino acid composition: 
Ala (A)  19	 13.5%
Arg (R)   5	  3.5%
Asn (N)  10	  7.1%
Asp (D)   5	  3.5%
Cys (C)   1	  0.7%
Gln (Q)   3	  2.1%
Glu (E)   8	  5.7%
Gly (G)   9	  6.4%
His (H)   1	  0.7%
Ile (I)  13	  9.2%
Leu (L)   9	  6.4%
Lys (K)  13	  9.2%
Met (M)   5	  3.5%
Phe (F)   4	  2.8%
Pro (P)  11	  7.8%
Ser (S)   7	  5.0%
Thr (T)   7	  5.0%
Trp (W)   0	  0.0%
Tyr (Y)   1	  0.7%
Val (V)  10	  7.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 18

Atomic composition:

Carbon      C	       663
Hydrogen    H	      1100
Nitrogen    N	       184
Oxygen      O	       196
Sulfur      S	         6

Formula: C663H1100N184O196S6
Total number of atoms: 2149

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     1490
Abs 0.1% (=1 g/l)   0.099, assuming all pairs of Cys residues form cystines


Ext. coefficient     1490
Abs 0.1% (=1 g/l)   0.099, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.00
This classifies the protein as unstable.



Aliphatic index: 94.89

Grand average of hydropathicity (GRAVY): -0.059