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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MALDSVKHLP IHGVSAFSSV TVEIKSFFST VKPRKTSTFV YAFVVTFVAL TVFLAFSPSP

70 80 90 100 110 120
ITVALAPSIS SYVLPNITVS NSSNSSPSSL DSNFTTLRTP APENLTAVTK NLTFESPVAN

130 140 150 160 170 180
GTTDTNAKTI TIQFQTGHAK ENISCPDNKT ARDLDTHGAR KAPLSEVLAV NSTASPKRKQ

190 200 210 220 230 240
RRKSSLRKVI ESLKSCEFFE GDWVKDDSYP LYKPGSCNLI DEQFNCISNG RPDVDFQKLK

250 260 270 280 290 300
WKPKQCSLPR LNGGKLLEMI RGRRLVFVGD SLNRNMWESL VCILKGSVKD ESQVFEAHGR

310 320 330 340 350 360
HQFRWEAEYS FVFKDYNCTV EFFASPFLVQ EWEVTEKNGT KKETLRLDLV GKSSEQYKGA

370 380 390 400 410 420
DILVFNTGHW WTHEKTSKGE DYYQEGSTVH PKLDVDEAFR KALTTWGRWV DKNVNPKKSL

430 440 450 460 470 480
VFFRGYSPSH FSGGQWNAGG ACDDETEPIK NETYLTPYML KMEILERVLR GMKTPVTYLN

490 500 510 520 530 540
ITRLTDYRKD AHPSIYRKQK LSAEESKSPL LYQDCSHWCL PGVPDSWNEI FYAELLVKLD

550
QLGGKRRRKA LKDHRS


References and documentation are available.

Number of amino acids: 556 Molecular weight: 63004.59 Theoretical pI: 9.06
Amino acid composition: 
Ala (A) 29 5.2% Arg (R) 29 5.2% Asn (N) 26 4.7% Asp (D) 29 5.2% Cys (C) 10 1.8% Gln (Q) 15 2.7% Glu (E) 34 6.1% Gly (G) 29 5.2% His (H) 13 2.3% Ile (I) 19 3.4% Leu (L) 49 8.8% Lys (K) 47 8.5% Met (M) 6 1.1% Phe (F) 29 5.2% Pro (P) 29 5.2% Ser (S) 54 9.7% Thr (T) 40 7.2% Trp (W) 12 2.2% Tyr (Y) 17 3.1% Val (V) 40 7.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 63 Total number of positively charged residues (Arg + Lys): 76 Atomic composition: Carbon C 2825 Hydrogen H 4395 Nitrogen N 769 Oxygen O 835 Sulfur S 16 Formula: C2825H4395N769O835S16 Total number of atoms: 8840 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 91955 Abs 0.1% (=1 g/l) 1.459, assuming all pairs of Cys residues form cystines Ext. coefficient 91330 Abs 0.1% (=1 g/l) 1.450, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.16 This classifies the protein as unstable. Aliphatic index: 73.78 Grand average of hydropathicity (GRAVY): -0.489