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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MALEAMNTPT SSFTRIETKE DLMNDAVFIE PWLKRKRSKR QRSHSPSSSS SSPPRSRPKS

70 80 90 100 110 120
QNQDLTEEEY LALCLLMLAK DQPSQTRFHQ QSQSLTPPPE SKNLPYKCNV CEKAFPSYQA

130 140 150 160 170 180
LGGHKASHRI KPPTVISTTA DDSTAPTISI VAGEKHPIAA SGKIHECSIC HKVFPTGQAL

190 200 210 220 230 240
GGHKRCHYEG NLGGGGGGGS KSISHSGSVS STVSEERSHR GFIDLNLPAL PELSLHHNPI

250 260 270
VDEEILSPLT GKKPLLLTDH DQVIKKEDLS LKI


References and documentation are available.

Number of amino acids: 273 Molecular weight: 29795.71 Theoretical pI: 8.67
Amino acid composition: 
Ala (A) 15 5.5% Arg (R) 12 4.4% Asn (N) 8 2.9% Asp (D) 11 4.0% Cys (C) 6 2.2% Gln (Q) 11 4.0% Glu (E) 18 6.6% Gly (G) 18 6.6% His (H) 14 5.1% Ile (I) 15 5.5% Leu (L) 26 9.5% Lys (K) 21 7.7% Met (M) 4 1.5% Phe (F) 6 2.2% Pro (P) 22 8.1% Ser (S) 36 13.2% Thr (T) 16 5.9% Trp (W) 1 0.4% Tyr (Y) 4 1.5% Val (V) 9 3.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 29 Total number of positively charged residues (Arg + Lys): 33 Atomic composition: Carbon C 1296 Hydrogen H 2086 Nitrogen N 378 Oxygen O 407 Sulfur S 10 Formula: C1296H2086N378O407S10 Total number of atoms: 4177 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 11835 Abs 0.1% (=1 g/l) 0.397, assuming all pairs of Cys residues form cystines Ext. coefficient 11460 Abs 0.1% (=1 g/l) 0.385, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 72.68 This classifies the protein as unstable. Aliphatic index: 73.63 Grand average of hydropathicity (GRAVY): -0.611